Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice, Tom Wallace, Amy E. Harwood, and Ian C. Chetter, Hull, United Kingdom – Diabetes mellitus is one of the most common chronic diseases worldwide. Diabetic foot ulcers (DFUs) occur in over 10% of diabetic patients and are associated with high morbidity. Clinical trials have shown benefit from extracorporeal shockwave therapy (ESWT) in a DFU healing. This systematic review aims to assess the currently available evidence examining the efficacy of ESWT on healing of DFU.