SoftWave Research

Newest Research

Seven Trends in Healing for 2023

Smith, William The pace of innovation in regenerative medicine keeps getting faster. At clinics across...

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Placebo controlled double-blinded, prospectively randomized clinical trial with 17 patients (11 verum, 5 placebo) for evaluation of cellulitetreatment with Acoustic Wave Therapy, (AWT(®))...

Cleveland Clinic – Low Intensity Shockwaves In Urology

Cleveland Clinic Daniel Shoskes, MD – As urologists, we have decades of experience with extracorporeal shockwave lithotripsy for...

Acoustic Field of a Ballistic Shock Wave Therapy Device

Abstract—Shock wave therapy (SWT) refers to the use of focused shock waves for treatment of...

MTS Science White Paper – Softwave – Pain Therapy

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Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

MTS Science 2016. Urogenital indications such as painful penile angulation, erection problems and / or chronic...

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Department of Plastic, Aesthetic and Reconstructive Surgery and Burn Center Vall d’Hebron University Hospital, Autonomous...

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

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The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Rani S, Ritter T – Wound healing is a complex process and often delayed in patients with...

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Falkensammer et al.Clin Oral Investig. 2014 Dec;18(9):2187-92. doi: 10.1007/s00784-014-1199-0. Click here to read more.

Physical Rehabilitation Using Shockwave Therapy

Injuries can have a serious impact on lifestyle and health, which means that physical rehabilitation...

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

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Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

(Non-invasive treatment of herniated discs by focused shockwave therapy) – In orthopedic practice meets a number...

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping and localized fat

Systematic review. – Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and...

Veterinary wound care case study

The following images are of dog bites wounds sustained by a foal approximately one week...

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Van der Jagt et al.Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society,...

Shock wave therapy for osteoinduction

Koolen et al. 20th ISMST Congress in San Sebastian, Spain Abstract P33 Click here to...

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

2016 Dietz-Laursonn Click here to read more.

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

SoftWave® Tissue Regeneration Technologies, a disruptive bio-medical device company, announces the beginning of a trial...

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

Wound healing disorders after vein harvesting for coronary artery bypass graft surgery increase morbidity and...

The effect of shock waves on in vitro cartilage development in silk scaffolds

Szwarc et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Extracorporeal Shock Wave Therapy: Current Evidence

The aim of this article is to provide a concise review of the basic science...

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

(Department of Physical Therapy, Youngdong University) – [Purpose] The purpose of the present study was to...

Penile low-intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic erectile dysfunction since 2-10 years: A prospective, randomized, placebo-controlled study

Vinay et al., Fundació Puigvert, Barcelona, Spain 20th ISMST Congress in San Sebastian, Spain Click...

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Peyronie’s Disease (PD), and Sexual Rehabilitation After Radical Prostatectomy With Special Focus on Technical Aspects...

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Knowing the most effective treatment options for your patients is crucial for their speedy recovery....

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

(MTS Science) – Peripheral nerve injuries affect millions of people every year. After trauma or surgery, patients...

Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...

Shock wave therapy alone has no impact on cancer growth

Cancer remains one of the leading causes of morbidity and mortality throughout the world. Several...

The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

High energy diaphyseal fractures constitute a complicated matter for trauma units and urgent medical and...

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Zins et al.Angiogenesis, 13(4), 293–304. https://doi.org/10.1007/s10456-010-9186-9. Abstract Impaired wound healing is a persistent clinical problem which...

Shock wave treatment for in vitro engineering applications

Weihs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

ESWT Therapy for Treatment of Keloid Scars

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Shockwave Therapy: Does it Hurt?

At SoftWave we promote healing using shockwave therapy. SoftWave strives to make patients’ lives easier...

Exclusive Distribution Agreement With Cynosure – Aesthetics and Sexual Health Markets

Exclusive agreement to supply Cynosure LLC, a global leader in medical aesthetics, with its patented...

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

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Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...

Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

The use of non-invasive brain therapies has become a hot topic recently. Alzheimer’s and Parkinson’s...

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

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Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Urology Section, Department of Surgery, University of Catania, Catania, Department of Urology, University of Florence, Andrology...

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Bhojani et al.J. Urol. (2015). doi:10.1016/j.juro.2014.09.117. Click here to read more.

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Journal of Sexual Medicine (Guiting Lin MD PhD, Amanda B. Reed-Maldonado MD, Bohan Wang MD,...

Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

In this prospective design study the effects of low-energy partially focusedextracorporeal generated shock waves (ESW)...

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Patients with probable Alzheimer disease (AD) had sustained memory improvements months after ultrasound brain stimulation...

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Paul Slezak ISMST 2017 San Sebastian Click here to read more.

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Director Kompass Health Associates, Centre for Regenerative Health, Sports Performance & Research – Auckland, New...

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Holfeld et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

A. SKOLARIKOS, M.D., ALARGOF, M.D., RIGAS, M.D., DELIVELIOTIS, M.D. and E. KONSTANTINIDIS, M.D – To assess in...

Efficacy of Unfocused Medium-Intensity Extracorporeal Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Extracorporeal shock wave therapy (ESWT) is a promising treatment for plantar fasciitis (PF), however, treatment...

Ultrasound Based Brain Stimulation

Ultrasound based brain stimulation techniques bay become a powerful new technique to modulate the human...

DermaGold100 Wound care Meta Analysis -(Philip Lavin Phd)

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SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

ATLANTA, May 19, 2021 (Newswire) – SoftWave Tissue Regeneration Technologies patented extracorporeal shock wave device called...

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Low-energy extracorporeal shock wave treatment (ESWT) is a relatively new therapeutic tool that is widely...

4 U. S. Patents issued on July 19, 2022

SoftWave officially has been granted 4 new patents as of July 19, 200. They include...

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...

Best Shockwave Therapy Machine For Providers

Extracorporeal shockwave therapy (ESWT) is a viable, growing treatment option for patients who are seeking...

Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant...

Benefits of Unfocused Li-ESWT for Erectile Dysfunction and Nocturia

When health issues arise, it is crucial to know what treatment options are available and...

CLEARANCES

Lithotriptor, Extracorporeal Shock-Wave, Urological – LithoGoldMassager, Therapeutic, Electric – DermaGold; OrthoGold; UroGoldMassager, Therapeutic, Electric –...

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...

Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

Chronic muscle pain syndrome is one of the main causes of musculoskeletal pathologies requiring treatment....

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

National Institutes of Health (Xin Zhang, James D. Krier, Carolina Amador Carrascal, James F. Greenleaf, Behzad...

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

The stromal vascular fraction (SVF) is a heterogeneous cell population derived from the adipose tissue....

Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

This study aimed to evaluate the therapeutic effects of Low intensity extracorporeal low energy shock...

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

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Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Tissue Regeneration Technologies – A four patient pilot trial was conducted in 2018 including four...

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

The current ‘‘gold standard’’ for treatment of chronic fracture nonunion in the metaphyseal-diaphyseal region of...

Novel Approach to Obtain an Activated Fat Graph

One of the mainstays of facial rejuvenation strategies is volume restoration, which can be achieved...

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Saggini et al. Int J Pharma Sci Res 2016, 3: 119 Click here to read more.

Benefits of Spark Wave Therapy in neuronal regeneration

(MTS Science) – Extracorporeal shock wave therapy (ESWT) is widely used in clinical practice. In addition to...

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

This study investigated the plasma protein expression in the extracorporeal shock wave therapy group and...

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

Sudhanshu Chitale, Mohammed Morsey, Louise Swift* and Krishna Sethia Department of Urology, Norfolk & Norwich...

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis

The goal for treating osteoarthritis (OA) is finding ways to decrease joint pain and dysfunction...

Set up Instructions

Video for setting up the device, inserting the applicator and water cartridge, and how to...

STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new...

Best Treatments for Tennis Elbow Relief

The road to recovery is not always easy, but SoftWave wants to make it as...

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Graber et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Influence of medical shock waves on healthy muscle tissue

Competitive sport requires each athlete to be at peak performance at all times. This is...

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and...

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Platelet-rich plasma (PRP) and extracorporeal shockwave therapy (ESWT) are both used for the treatment of...

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

The objective of this study is to demonstrate the efficacy and safety of AWT(®), combining two different mechanical...

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Research Institute of Environmental Medicine at Heinrich-Heine University, D-40021 Duesseldorf,Germany In vivo measurements in 26...

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Dental implants are a routine procedure within the therapeutic range of dentists. Many loading protocols...

Spark Wave® Therapy Ameliorates Urinary Incontinence

MTS-Science April 14th, 2019. Stress urinary incontinence (SUI) is the involuntary leakage of urine during activities such...

Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

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Efficacy of extracorporeal shockwave therapy (ESWT) for male chronic pelvic pain syndrome: a phase III, randomized, double blind controlled with placebo study 

Ramon et al., Hospital Quiron Barcelona, Spain 20th ISMST Congress in San Sebastian, Spain.Poster Session...

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease – A new navigated focal brain therapy

Ultrasound-based brain stimulation techniques offer an exciting potential to modulate the human brain in a...

LL37 and shock waves

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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Thayná Melo de Lima Morais, Patrícia Froes Meyer, Liliane Santos de Vasconcellos, Julio Costa e Silva, Ito Ferreira e...

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Schaden W, Thiele R, Kolpl C, et al.J Surg Res. 2007; 143:1-12 Click here to read...

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...

Shockwave Therapy Helping Patients With Peripheral Artery Disease

CBS News Stephanie Stahl reports. (Video) Click here to view video.

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

A Systematic Scoping Review of Pre-Clinical Studies – Using Cochrane’s methodologic recommendations on scoping studies and...

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

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Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...

Extracorporeal shockwave therapy for treatment of keloid scars

Center for Shockwave Medicine and Tissue Engineering, Department of Orthopedic Surgery/Sports Medicine, Kaohsiung Chang Gung...

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Yard DH.Renal & Urology News. 2011 Click here to read more.

Optimization of screw fixation in rat bone with extracorporeal shock waves

Koolen et al.Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23615. Click here to read more.

Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

This study determined the effect of electrohydraulic extracorporeal shockwave therapy (ESWT) on the healing of...

Zapping chronic tendon pain

Click here to read more.

Exosomes and Cardiovascular Protection

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called...

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Extracorporeal shock wave treatment has been used successfully for the treatment of avascular necrosis of...

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

CREST syndrome is a variant of systemic sclerosis, which affects a relatively small number of...

Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Antonic et al., 2018Wound medicine 20 (2018) 1-6https://doi.org/10.1016/j.wndm.2017.11.0012018 Click here to read more.

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and has presented...

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

We prospectively studied extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder in...

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD, Bernd Hartmann, MD, Josh Tyler, MD, Heike Maier, MD, Richard Thiele, MD,Wolfgang...

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Schaden W, Mittermayr R.Jatros Orthopädie & Rheumatologie. 5/2011; 72-74 Click here to read more.

Shockwave therapy in stress fractures

Stress fractures are common painful conditions in athletes, usually associated to biomechanical overloads. Low risk stress...

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Stojadinovic A, Elster E, Anam EA, et al.Angiogenesis. 2008; 11(4):369-380 Click here to read more.

Shockwave Therapy for the Treatment of Cancer

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The speed...

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Mayo Clinic – Extracorporeal shock wave therapy (ESWT) is a noninvasive treatment that involves delivery of shock...

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy.

Quadlbauer et al.Arch Orthop Trauma Surg. 2019 Feb;139(2):281-293.2019 Click here to read more.

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

d’Agostino MC., Sukubo NG., Tibalt W., Respizzi S., Locati M.,Int J Surg. 2015 Dec; 1-72015 Click...

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

he physical shaking of the tissue by the shock waves leads to a mechanotransduction; the...

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

For almost 30 years, extracorporeal shock wave therapy has been clinically implemented as an effective...

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

Postischemic cardiomyopathy remains one of the disorders in urgent need of effective noninvasive therapy. It...

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous...

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, inflammatory response leading...

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Zimpfer D, Aharinejad S, Holfeld J, et al.J Thorac Cardiovasc Surg. 2009; 137(4):963-970 Click here to...

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Maria Cristina D’Agostino, Simona Maria Carmignano, and Andrea Saggini Click here to read more.

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Hexsel D, Camozzato FO, Silva AF, Siega Cellulite is a commonality among most women and some men. As...

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

(Alexandra Aicher, MD; Christopher Heeschen, MD; Ken-ichiro Sasaki, MD; Carmen Urbich, PhD; Andreas M. Zeiher,...

Antibacterial effects of extracorporeal shock waves

Klinik und Poliklinik für Orthopädie und Sportorthopädie der Technischen Universität München, München, Germany; and Institut...

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The...

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Extracorporeal shockwave therapy (ESWT) is used in a number of indications in the medical field....

Indications for shockwaves in veterinary medicine

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TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

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Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into...

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

A systematic review and meta-analysis of preclinical studies – Limited regeneration after nerve injury often leads...

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Swarc et al. 20th ISMST Congress in San Sebastian, Spain Abstract P28 Click here to...

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

PRESS RELEASE PR Newswire 2018 – Comprehensive Urology Medical Group, one of the nation’s leading...

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Wolff et al.Ultrasound Med Biol. 2011 Jul;37(7):1111-9. Click here to read more.

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

(Dr Irwin Goldstein MD) Analogy to blood flow imparting physical forces – shear stress – onto...

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Ottomann C., Antonic V., Münch S., et al.J Bioengineer & Biomedical Sci 2015, 6:12015 Click here...

Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

Seventy-two patients with 72 chronic diabetic foot ulcers were randomly divided into two groups of...

Alternative Treatment for Erectile Dysfunction with the Urogold 100™

MTS Science Published on Jun 21, 2016 – The improvement of Erectile Dysfunction through the treatment with...

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Falkensammer et al.Am J Orthod Dentofacial Orthop. 2014 Oct;146(4):413-22. doi: 10.1016/j.ajodo.2014.06.008. Click here to read...

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany)

The aim of this meta analysis was to investigate the effectiveness of extracorporeal shock wave...

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...

Molecular changes in diabetics foot ulcers

The Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College...

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Elliot B. Lander, MD, Mark H. Berman, MD, Jackie R. See, MD – This pilot study...

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice,...

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Mittermayr R, Antonic V, Hartinger J et al .Wound Repair Regen. 2012 Jul;20(4):456-65 Click here to...

Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

The main aim of our research in this field is to regenerate infarcted myocardium, respectively...

Analysis of treatment protocols: application of ESWT for wound healing disorders

Shock waves are high-energy acoustic waves characterized by an initial rise of high pressure within...

ESWT for Acute and Chronic Soft Tissue Wounds

Wolfgang Schaden, M.D., Richard Thiele, M.D., Christine Kölpl, M.D., Michael Pusch, M.D., Aviram Nissan, M.D.,...

Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Human bone marrow stromal cells (hBMSCs) bear tremendous clinical potential due to their immunomodulatory properties...

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...

SDSM Spine pain protocol

Angiogenic response upon shock wave treatment of the ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Nowadays, the search for the ideal body is related to internal dissatisfactions that generate low...

Case Series of Weekly Low Intensity Shockwave Therapy for Erectile Dysfunction

Shoskes et al., Cleveland Clinic, United States 20th ISMST Congress in San Sebastian, Spain Abstract...

Scientific Reports – Gene transfection by shock waves

Extracorporeal shock wave (SW) therapy has been studied in the transfection of naked nucleic acids...

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Enhancement of flap survival through extracorporeal shock wave treatment (ESWT) is a promising new technique;...

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

It was found a statistically significant difference between the study groups and control group in...

Athletic therapy (Mts-Science)

In modern society today, sport activity is becoming increasingly important. Reasons include more free time,...

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

Shockwave therapy was originally developed to disintegrate urinary stones 4 decades ago1 . Since then,...

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

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A meta-analysis of extracorporeal shock wave therapy for Peyronie’s disease – (International Journal of Impotence Research 2016) – Peyronie’s disease (PD) is a relatively common disorder originating from connective tissue and characterized by progressively fibrotic plaques in the penile tunica albuginea.

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Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal...

Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost...

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Feichtinger et al.Am J Sports Med. 2019 Jul;47(9):2158-2166.2019 Click here to read more.

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

This study aimed to investigate PDL’s cytokine concentration fluctuations after induction of orthodontic force with...

TRT SoftWaves® – a new regenerative therapy for paraplegia

Extracorporeal softwave therapy (ESWT) is widely used in clinical practice. In addition to its original...

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

American Urological Association 2017 – American Urological Association. Dr. Tom Lue addressing erectile dysfunction during...

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Van der Jagt et al.Journal of Orthopaedic Research, 31(5), 768–775. https://doi.org/10.1002/jor.22258. Click here to read more.

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Erectile dysfunction is highly prevalent in type II diabetes mellitus.Low intensity extracorporeal shock wave therapy...

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Fuchs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...

MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and...

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

It has been hypothesized that there are two mechanisms of acute traumatic spinal cord injury...

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Cyrill Slezak Beijing, May 24TH, 2019 Click here to read more.

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Tepeöylü et al.Journal of Tissue Engineering and Regenerative Medicine, 12(1), e486–e494. https://doi.org/10.1002/term.2317.2018 Click here to read...

Dr Irwin Goldstein Dinner Presentation – Nashville

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MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process...

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

She was treated with high dose antibiotics. Surgeons recommended a colostomy and several operations to...