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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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softwave device with water water blue background

What are the Side Effects of SoftWave Therapy

Spark Wave® Therapy Improves Full Thickness Skin Defects

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Shockwave Therapy for Plantar Fasciitis

Erectile Dysfunction before and after results under ultrasound

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Extracorporeal Shock Wave Therapy: Current Evidence

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

ISSWSH Abstract

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Natural Remedies for Tendonitis

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines: Cost, Efficacy, & Alternatives

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Neuropathy

Shockwave Therapy for Neuropathy

Shock waves promote spinal cord repair via TLR32

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Shockwave Therapy for Achilles Tendonitis

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Extracorporeal Shock Wave Device for Treatment of Chronic Burns

MTS Spark Wave Publications – Science Telegram

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Alternatives to Surgery

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal Shockwave Therapy for Arthritis Treatment

Mechano-transduction effect of shock waves

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Is surgery the only option for bone-on-bone?

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How Shockwave Therapy Breaks Down Scar Tissue

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Optimization of screw fixation in rat bone with extracorporeal shock waves

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Scientific Reports – Gene transfection by shock waves

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

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Reduce Inflammation Naturally With Shockwave Therapy

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Athletic therapy (Mts-Science)

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

How Does Shockwave Therapy Work?

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Using Sound to Battle Opioid Crisis

Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

Acoustic wave therapy for cellulite, body shaping and fat reduction.

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

​Prospective randomized phase II trial of accelerated reepithelialization

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal Magnetic Transduction Therapy Explained

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Ultrasound Based Brain Stimulation

Biological mechanism of shockwave in bone

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Influence of medical shock waves on healthy muscle tissue

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Cleveland Clinic – Low Intensity Shockwaves In Urology

Latest Basic Research Abstracts

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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Heart Regeneration becomes Reality!

MTS Science White Paper – Softwave – Pain Therapy

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Alternative Treatment using Shockwave for Erectile Dysfunction

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

EPAT Therapy Costs for Patients & Practices

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Peripheral Nerve Regeneration

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

The Roll of Spark Waves in the Management of Chronic Wounds.

Fully healed, Ordonez flourished for Tigers using ESWT

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

LL37 and shock waves

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Benefits of Spark Wave Therapy in neuronal regeneration

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Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

Shock Waves Reach Dental Implantology (Spanish)

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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Novel Approach to Obtain an Activated Fat Graph

Shockwave therapy in stress fractures

Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Motor and Sensory Schwann Cell Phenotype

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Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

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How to Manage Pain Without Drugs

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Acoustic Field of a Ballistic Shock Wave Therapy Device

SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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SoftWave Therapy for Knees

SoftWave Therapy for Knees

Managing Pain with Shockwave Therapy for Muscles

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Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

ISMST (International Society for Medical Shockwave Treatment)

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

Veterinary wound care case study

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

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Extracorporeal shock wave therapy: clinical applications and regulation

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

The link between shockwaves and innate immunity – the main working mechanism?

AUVA letter‒ Successful treatment of delayed and non-union fractures

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Shockwave Therapy for the Treatment of Cancer

Extracorporeal shockwave therapy induces alveolar bone regeneration

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Plantar Fasciitis Medical Devices That Relieve Pain

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ESWT minimizes ischemic tissue necrosis…

Biological mechanism of musculoskeletal shockwaves

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EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

Best Treatment for Tennis Elbow Relief

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Extracorporeal Shock Wave Therapy

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

ESWT for Acute and Chronic Soft Tissue Wounds

Treatment for osteonecrosis of the femoral head

Doubts over heart stem-cell therapy

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Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Shock waves promote spinal cord repair via TLR3

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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ESWT for retracting scars of the hand

Shockwave Therapy Of The Heart​

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Softwave vs radial

Radial Shockwave Therapy Machines Compared 

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Spark Wave® Therapy Ameliorates Urinary Incontinence

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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