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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
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SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Extracorporeal shock wave therapy for nonunion of the tibia

Cellular mechanotransduction: putting all the pieces together again

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Alternative Treatment using Shockwave for Erectile Dysfunction

Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

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Spark Wave® Therapy Ameliorates Urinary Incontinence

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Best Shockwave Machine for Providers

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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

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Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Softwave vs radial

Radial Shockwave Therapy Machines Compared 

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

Analysis of treatment protocols: application of ESWT for wound healing disorders

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Piezowave Shockwave Therapy vs Other Shockwave Devices

Piezowave Shockwave Therapy vs Other Shockwave Devices

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

ESWT for resident stress fractures in athletes.

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Treatment of stress urinary incontinence

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Urological Times Cover – Scroll to Page 18 – 19

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Macrophage migration induces angiogenesis

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Mechano-transduction effect of shock waves

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Shock Waves Reach Dental Implantology (Spanish)

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Scientific Reports – Gene transfection by shock waves

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

SoftWave Therapy Averts Amputation for Former College Football Coach

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MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

ESWT for Acute and Chronic Soft Tissue Wounds

Lohse – Busch ISMST Presentation

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

The Clinician’s Guide to Shockwave Therapy- Evidence, Safety, and Technology

The Clinician’s Guide to Shockwave Therapy: Evidence, Safety, and Technology

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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Motor and Sensory Schwann Cell Phenotype

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Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Extracorporeal Shockwave Therapy for Arthritis Treatment

Shock waves promote spinal cord repair via TLR3

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Treatment of scaphoid waist nonunion

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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The Roll of Spark Waves in the Management of Chronic Wounds.

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

SoftWave vs Shockwave Technology Explained 

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Best Treatment for Tennis Elbow Relief

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

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COVID-19 pneumonia: different respiratory treatment for different phenotypes?

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Extracorporeal Shock Wave Therapy: Current Evidence

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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10 Natural Ways to Find Pain Relief

Mesenchymal stem cells: Myths and reality

low intensity softwave in use on arm on a table

What Is Li-ESWT & How Does It Work?

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Spark Wave® Therapy Improves Full Thickness Skin Defects

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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Zapping chronic tendon pain

Indications for shockwaves in veterinary medicine

​Extracorporeal shock wave therapy in periodontics: A new paradigm

How Shockwave Therapy Breaks Down Scar Tissue

AUVA letter‒ Successful treatment of delayed and non-union fractures

Effects of ESWT on glycosaminoglycan expression during bone healing

Shock wave therapy alone has no impact on cancer growth

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

EPAT Therapy Costs for Patients & Practices

ESWT Therapy for Treatment of Keloid Scars

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

Shock waves promote spinal cord repair via TLR32

Shockwave Therapy for Calcific Tendonitis

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

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International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

Extracorporeal shock wave therapy: clinical applications and regulation

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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ESWT in skin & aesthetic indications

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Fully healed, Ordonez flourished for Tigers using ESWT

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Erectile Dysfunction before and after results under ultrasound

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Shockwave Therapy: Does it Hurt?

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Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

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Test43212

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

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Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Equine extracorporeal shock wave therapy

Shock wave treatment for in vitro engineering applications

ISSWSH Abstract

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Natural Remedies for Tendonitis

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Physical Rehabilitation Using Shockwave Therapy

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Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Low Intensity Shockwave Therapy vs High Intensity: Which Works Best?

softwave device with water water blue background

What are the Side Effects of SoftWave Therapy

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal Magnetic Transduction Therapy Explained

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Dr Irwin Goldstein Dinner Presentation – Nashville

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Using Sound to Battle Opioid Crisis

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Molecular changes in diabetics foot ulcers

Shockwave Therapy Of The Heart​

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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