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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

The link between shockwaves and innate immunity – the main working mechanism?

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Effects of Low-Energy Shock Waves on Oral Bacteria

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Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

Mechano-transduction effect of shock waves

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In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Motor and Sensory Schwann Cell Phenotype

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Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

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Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

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Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Plantar Fasciitis Medical Devices That Relieve Pain

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Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Shock wave treatment for in vitro engineering applications

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Reduce Inflammation Naturally With Shockwave Therapy

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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IVSWT Water Bath V2.0 Manual

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Best Treatment for Tennis Elbow Relief

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Spark Wave® Therapy Improves Full Thickness Skin Defects

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Shock Waves Reach Dental Implantology (Spanish)

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

Fully healed, Ordonez flourished for Tigers using ESWT

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Athletic therapy (Mts-Science)

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Biological mechanism of shockwave in bone

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Acoustic Field of a Ballistic Shock Wave Therapy Device

Shock wave therapy for systemic sclerosis

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MTS Spark WaveTM Technology and its mechanism of action in wound management

Influence of medical shock waves on healthy muscle tissue

Current concepts of shockwave therapy in stress fractures

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Shockwave Therapy for Calcific Tendonitis

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

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Shockwave Therapy for Plantar Fasciitis

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

MTS Spark Wave Publications – Science Telegram

Alternatives to Cortisone Shots

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Benefits of Spark Wave Therapy in neuronal regeneration

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Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

How to Manage Pain Without Drugs

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

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ESWT for resident stress fractures in athletes.

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

ESWT for Acute and Chronic Soft Tissue Wounds

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

How Does Shockwave Therapy Work?

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

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Extracorporeal shockwave therapy for treatment of keloid scars

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Cellular mechanotransduction: putting all the pieces together again

Principles of Shock Wave Therapy

Biological mechanism of musculoskeletal shockwaves

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Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

ESWT for retracting scars of the hand

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Latest Basic Research Abstracts

Scientific Reports – Gene transfection by shock waves

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Shock wave treatment of muscle stem cells – a new implementation for regeneration

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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10 Natural Ways to Find Pain Relief

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

Shockwave Therapy Of The Heart​

SoftWave vs Shockwave Technology Explained 

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Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines: Cost, Efficacy, & Alternatives

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Mesenchymal stem cells: Myths and reality

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Shock wave treatment enhances stemness and preserves multipotency

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Acoustic wave therapy for cellulite, body shaping and fat reduction.

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

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Shockwave therapy in stress fractures

Novel Approach to Obtain an Activated Fat Graph

Shock waves promote spinal cord repair via TLR32

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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Managing Pain with Shockwave Therapy for Muscles

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Optimization of screw fixation in rat bone with extracorporeal shock waves

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Erectile Dysfunction before and after results under ultrasound

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Treatment of stress urinary incontinence

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Peripheral Nerve Regeneration

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Shock waves promote spinal cord repair via TLR3

Treatment for osteonecrosis of the femoral head

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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How Shockwave Therapy Breaks Down Scar Tissue

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

ESWT minimizes ischemic tissue necrosis…

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Physical Rehabilitation Using Shockwave Therapy

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Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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