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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Biological Principles – Mechanotransduction

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Effect of shockwave therapy on orthodontic tooth movement

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Heart Regeneration becomes Reality!

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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Shock wave therapy alone has no impact on cancer growth

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Influence of medical shock waves on healthy muscle tissue

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Best Noninvasive Options for Regenerative Back Treatment Without Injections

Best Options for Regenerative Back Treatment Without Injections

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The Roll of Spark Waves in the Management of Chronic Wounds.

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Urological Times Cover – Scroll to Page 18 – 19

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

TRT SoftWaves® – a new regenerative therapy for paraplegia

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Neck ache treatment essentials: massage pillow, essential oil, towel, exercise bands, and relaxation guide.

Neck Ache Treatment: 7 Safe Ways to Find Relief

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

How to Manage Pain Without Drugs

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Comparing Shockwave Technologies for Treating Diabetic Foot Ulcers

A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Shockwave treatment enhances cell proliferation and improves wound healing

The Applied Mechanical Vibration as Extracorporeal Shock Wave

How to Improve Podiatry Practice ROI

Doctor Uses Shockwave Therapy to Heal Nearly Severed Foot

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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Macrophage migration induces angiogenesis

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

CM Shockwave Before And After Use

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Cellular mechanotransduction: putting all the pieces together again

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Provider demonstrating SoftWave TRT technology during a clinical treatment

Adding SoftWave TRT to Your Healthcare Practice

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Extracorporeal shock wave therapy: clinical applications and regulation

Managing Pain with Shockwave Therapy for Muscles

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Molecular changes in diabetics foot ulcers

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Latest Basic Research Abstracts

Test43212

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Shock waves promote spinal cord repair via TLR32

Technology Assessment “Wound Care” dermagold100

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

10 Natural Ways to Find Pain Relief

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Using acoustic therapy to prevent opioid addiction.

MTS Spark Wave Publications – Science Telegram

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Indications for shockwaves in veterinary medicine

Radial Shockwave Therapy Machines Compared 

The Physics of Shock Wave Lithotripsy

Erectile Dysfunction before and after results under ultrasound

Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

The link between shockwaves and innate immunity – the main working mechanism?

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

Non-Surgical Alternatives for Degenerative Disc Disease Treatment

Non-Surgical Treatment Options for Degenerative Disc Disease

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Spark Wave® Therapy Improves Cardiac Function

SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

Current concepts of shockwave therapy in stress fractures

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Sound Frequency Healing: The Spark of Life

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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Foot application

Shockwave Therapy for Podiatrists: A Complete Guide

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Spark Wave® Therapy Improves Full Thickness Skin Defects

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Physical therapist guides muscle strain treatment exercises for a patient wearing an arm sling.

Muscle Strain Treatment: Safe Steps for Recovery

Cleveland Clinic – Low Intensity Shockwaves In Urology

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

The effect of shock waves on in vitro cartilage development in silk scaffolds

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Golfer’s Secret Weapon for Injury Prevention: SoftWave TRT

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The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Using Sound to Battle Opioid Crisis

Acoustic Field of a Ballistic Shock Wave Therapy Device

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Lohse – Busch ISMST Presentation

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

What Is a Focused Shockwave Therapy Machine?

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Shock wave therapy for systemic sclerosis

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Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

What Is Li-ESWT & How Does It Work?

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Extracorporeal shock wave therapy for nonunion of the tibia

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Zimmer enPulsPro Shockwave Machines-

Shockwave Therapy for Chiropractors: Complete Guide

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Shock wave treatment for in vitro engineering applications

ESWT for retracting scars of the hand

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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SoftWave Therapy Averts Amputation for Former College Football Coach

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Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Shock waves promote spinal cord repair via TLR3

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

ISSWSH Abstract

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Physical therapist guiding a woman through a leg exercise for sciatica pain.

Physical Therapy Treatment for Sciatica Pain: A Guide

Shock wave therapy cost comparison with money and joint pain symbols on a balance scale.

How Much Shock Wave Therapy Costs: Price Guide

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

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Provider’s Guide to Shockwave Therapy for Wound Care

Provider’s Guide to Shockwave Therapy for Wound Care

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Extracorporeal Shock Wave Therapy

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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