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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Shockwave Therapy for Achilles Tendonitis

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Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

Test12343

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

ISMST (International Society for Medical Shockwave Treatment)

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

7 Red Flags That Signal a Risky Shockwave Device

7 Red Flags That Signal a Risky Shockwave Device

Shock wave treatment enhances stemness and preserves multipotency

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Can cellulite be treated with low-energy extracorporeal shock wave therapy?

How to Manage Pain Without Drugs

Neuropathy

Shockwave Therapy for Neuropathy

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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The Clinician’s Guide to Shockwave Therapy- Evidence, Safety, and Technology

The Clinician’s Guide to Shockwave Therapy: Evidence, Safety, and Technology

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Extracorporeal shock wave therapy: clinical applications and regulation

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Dr. Lohse Bush, first brain treatments

Shock wave treatment for in vitro engineering applications

LL37 and shock waves

Shock wave therapy for systemic sclerosis

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Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Macrophage migration induces angiogenesis

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

Golfer’s Secret Weapon for Injury Prevention: SoftWave TRT

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Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Benefits of Spark Wave Therapy in neuronal regeneration

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The Physics of Shock Wave Lithotripsy

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Doubts over heart stem-cell therapy

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Extracorporeal shockwave therapy induces alveolar bone regeneration

Biological Principles – Mechanotransduction

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Erectile Dysfunction before and after results under ultrasound

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Shockwave Therapy for the Treatment of Cancer

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Extracorporeal shockwave therapy for treatment of keloid scars

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

CM Shockwave Before And After Use

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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AUVA letter‒ Successful treatment of delayed and non-union fractures

Lohse – Busch ISMST Presentation

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Mechano-transduction effect of shock waves

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Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

MTS Spark Wave Publications – Science Telegram

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

MTS Science White Paper – Softwave – Pain Therapy

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Effects of Low-Energy Shock Waves on Oral Bacteria

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Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Plantar Fasciitis Medical Devices That Relieve Pain

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Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Shockwave therapy in stress fractures

EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

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Extracorporeal shock waves, a new non-surgical method to treat severe burns

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Indications for shockwaves in veterinary medicine

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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SoftWave vs Shockwave Technology Explained 

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Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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SoftWave TRT vs Storz Shockwave Machines Compared

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Veterinary wound care case study

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

DolorClast Therapy- Mechanism, Indications, and Clinical Evidence

DolorClast Therapy: What Is It & Does It Work for Patients?

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

Shockwave Therapy for Calcific Tendonitis

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

Optimization of screw fixation in rat bone with extracorporeal shock waves

The link between shockwaves and innate immunity – the main working mechanism?

Shock wave therapy for osteoinduction

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Shock waves promote spinal cord repair via TLR32

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

EPAT Therapy for Plantar Fasciitis vs Alternatives

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

Best Noninvasive Options for Regenerative Back Treatment Without Injections

Best Options for Regenerative Back Treatment Without Injections

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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

4 U. S. Patents issued on July 19, 2022

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Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

​Extracorporeal shock wave therapy in periodontics: A new paradigm

ESWT in skin & aesthetic indications

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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Shock Waves Reach Dental Implantology (Spanish)

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

​Extracorporeal shock wave therapy: What? Why? Safety?

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

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Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Set up Instructions

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Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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