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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Extracorporeal Shock Wave Therapy

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

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Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Alternative Treatment using Shockwave for Erectile Dysfunction

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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MTS Spark WaveTM Technology and its mechanism of action in wound management

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Shock wave therapy for osteoinduction

Acoustic Wave Therapy vs Shockwave Therapy

Scientific Reports – Gene transfection by shock waves

The Clinician’s Guide to Shockwave Therapy- Evidence, Safety, and Technology

The Clinician’s Guide to Shockwave Therapy: Evidence, Safety, and Technology

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Angiogenic response upon shock wave treatment of the ischaemic muscle

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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COVID-19 pneumonia: different respiratory treatment for different phenotypes?

How Does Shockwave Therapy Work?

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Test43212

Non-Surgical Alternatives for Degenerative Disc Disease Treatment

Non-Surgical Treatment Options for Degenerative Disc Disease

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Shock waves induce angiogenesis via exosome release

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Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

ESWT in skin & aesthetic indications

Best Treatment for Tennis Elbow Relief

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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Shock wave treatment enhances stemness and preserves multipotency

The Best Alternatives to Rotator Cuff Surgery

Alternatives to Rotator Cuff Surgery

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Extracorporeal Shockwave Therapy for Arthritis Treatment

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

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Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Biological mechanism of shockwave in bone

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SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

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TRT SoftWaves® – a new regenerative therapy for paraplegia

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What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

MTS Spark Wave Publications – Science Telegram

Benefits of Spark Wave Therapy in neuronal regeneration

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Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Dr Irwin Goldstein Dinner Presentation – Nashville

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Biological Principles – Mechanotransduction

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Using Sound to Battle Opioid Crisis

SoftWave TRT vs Storz Shockwave Machines Compared

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Gainswave Machines: Cost, Efficacy, & Alternatives

SoftWave vs. GainsWave Therapy for ED and Beyond

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Effects of ESWT on glycosaminoglycan expression during bone healing

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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​Antibacterial effects of extracorporeal shock waves

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Novel Approach to Obtain an Activated Fat Graph

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Radial Shockwave Therapy Machines Compared 

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Evaluation of extracorporeal shock wave therapy for osteoarthritis

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Spark Wave® Therapy Improves Full Thickness Skin Defects

Extracorporeal shockwave therapy induces alveolar bone regeneration

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Effect of shock waves on macrophages

Equine extracorporeal shock wave therapy

Physical Rehabilitation Using Shockwave Therapy

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How Shockwave Therapy Breaks Down Scar Tissue

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

SoftWave vs Shockwave Technology Explained 

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Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Dr. Lohse Bush, first brain treatments

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

The effect of shock waves on in vitro cartilage development in silk scaffolds

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Fully healed, Ordonez flourished for Tigers using ESWT

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Ultrasound Brain Stimulation Piloted in Alzheimer Study

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Urological Times Cover – Scroll to Page 18 – 19

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

AUVA letter‒ Successful treatment of delayed and non-union fractures

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Biological mechanism of musculoskeletal shockwaves

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Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

Cleveland Clinic – Low Intensity Shockwaves In Urology

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Shockwave Therapy for Calcific Tendonitis

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

ESWT minimizes ischemic tissue necrosis…

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

10 Natural Ways to Find Pain Relief

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

Heart Regeneration becomes Reality!

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

EPAT Therapy Side Effects & Contraindications

Effects of Low-Energy Shock Waves on Oral Bacteria

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What are the Side Effects of SoftWave Therapy

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

Shock Waves Reach Dental Implantology (Spanish)

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Radial vs. Focused Shockwave Therapy: Clinical Deep Dive

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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How to Improve Podiatry Practice ROI

How to Improve Podiatry Practice ROI

Extracorporeal shockwave therapy for treatment of keloid scars

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Best Noninvasive Options for Regenerative Back Treatment Without Injections

Best Options for Regenerative Back Treatment Without Injections

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Reduce Inflammation Naturally With Shockwave Therapy

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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