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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Extracorporeal shock waves, a new non-surgical method to treat severe burns

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Expanding Non-Surgical Options in Podiatry Clinics

DolorClast Therapy- Mechanism, Indications, and Clinical Evidence

DolorClast Therapy: What Is It & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

The effect of shock waves on in vitro cartilage development in silk scaffolds

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Government Sales

Non-Surgical Alternatives for Degenerative Disc Disease Treatment

Non-Surgical Treatment Options for Degenerative Disc Disease

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

Heart Regeneration becomes Reality!

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Shock wave therapy for systemic sclerosis

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Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

4 U. S. Patents issued on July 19, 2022

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SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

StemWave Machine: Cost, Reviews & Alternatives for Practice Owners

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

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Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Shockwave Therapy Helping Patients With Peripheral Artery Disease

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Indications for shockwaves in veterinary medicine

Natural Remedies for Tendonitis

Foot application

Shockwave Therapy for Podiatrists: A Complete Guide

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Lohse – Busch ISMST Presentation

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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What Doctors Should Know About Storz Medical Shockwave

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

How to Improve Podiatry Practice ROI

How to Improve Podiatry Practice ROI

Latest Basic Research Abstracts

Is a Shockwave Therapy Machine for Home Use?

Macrophage migration induces angiogenesis

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

ESWT Therapy for Treatment of Keloid Scars

What Is a Focused Shockwave Therapy Machine?

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Spark Wave® Therapy Improves Full Thickness Skin Defects

EPAT Therapy for Plantar Fasciitis vs Alternatives

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Shock wave treatment enhances stemness and preserves multipotency

The link between shockwaves and innate immunity – the main working mechanism?

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Evaluation of extracorporeal shock wave therapy for osteoarthritis

​Extracorporeal shock wave therapy in periodontics: A new paradigm

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Reduce Inflammation Naturally With Shockwave Therapy

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Extracorporeal Shock Wave Therapy: Current Evidence

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Veterinary wound care case study

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Extracorporeal Magnetic Transduction Therapy Explained

EMTT vs. Shockwave Therapy: A Clinical Comparison for Providers

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Chattanooga Shockwave Devices Compared- What Clinicians Should Evaluate

Chattanooga Shockwave Therapy Devices Compared

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

Shockwave Therapy for the Treatment of Cancer

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

MTS Spark WaveTM Technology and its mechanism of action in wound management

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

How Does Piezoelectric Shockwave Compare to Electrohydraulic Shockwave for Clinical Use?

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

ESWT minimizes ischemic tissue necrosis…

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Doubts over heart stem-cell therapy

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The Best Alternatives to Rotator Cuff Surgery

Alternatives to Rotator Cuff Surgery

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

SoftWave vs Shockwave Technology Explained 

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Shock wave therapy alone has no impact on cancer growth

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Biological mechanism of shockwave in bone

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Cellular mechanotransduction: putting all the pieces together again

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Dr Irwin Goldstein Dinner Presentation – Nashville

Biological mechanism of musculoskeletal shockwaves

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Extracorporeal Shock Wave Therapy

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

ESWT for Acute and Chronic Soft Tissue Wounds

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Shockwave Therapy for Achilles Tendonitis

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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

​Antibacterial effects of extracorporeal shock waves

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

10 Natural Ways to Find Pain Relief

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Exploring Regenerative Treatment for Knees After Failed Conservative Care

Regenerative Treatment for Knees That Fail Conservative Care

Ultrasound Based Brain Stimulation

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Low Intensity Shockwave Therapy vs High Intensity: Which Works Best?

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

SoftWave Therapy Averts Amputation for Former College Football Coach

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MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

7 Red Flags That Signal a Risky Shockwave Device

Can Shockwave Therapy Cause Damage?

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

The Roll of Spark Waves in the Management of Chronic Wounds.

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

ISMST (International Society for Medical Shockwave Treatment)

AUVA letter‒ Successful treatment of delayed and non-union fractures

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

ESWT in skin & aesthetic indications

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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Extracorporal SoftWave Treatment to Improve Nerve Regeneration

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Sound Frequency Healing: The Spark of Life

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Zapping chronic tendon pain

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

Shock Waves Reach Dental Implantology (Spanish)

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Spark Wave® Therapy Improves Cardiac Function

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Comparing Shockwave Technologies for Treating Diabetic Foot Ulcers

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

​Exosomes and Cardiovascular Protection

Shockwave Therapy for Calcific Tendonitis

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Spark Wave® Therapy Ameliorates Urinary Incontinence

What Is Li-ESWT & How Does It Work?

​Prospective randomized phase II trial of accelerated reepithelialization

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

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Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Dr. Lohse Bush, first brain treatments

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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