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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Alternatives to Surgery

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Test43212

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Fully healed, Ordonez flourished for Tigers using ESWT

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Non-Surgical Alternatives for Degenerative Disc Disease Treatment

Non-Surgical Treatment Options for Degenerative Disc Disease

Is surgery the only option for bone-on-bone?

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Managing Pain with Shockwave Therapy for Muscles

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

How Shockwave Therapy Breaks Down Scar Tissue

Effect of shockwave therapy on orthodontic tooth movement

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Using acoustic therapy to prevent opioid addiction.

Shockwave treatment enhances cell proliferation and improves wound healing

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

What Is Piezowave and How Does It Work?

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Shock wave treatment enhances stemness and preserves multipotency

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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EPAT Therapy Side Effects & Contraindications

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Shock wave treatment for in vitro engineering applications

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Effects of Low-Energy Shock Waves on Oral Bacteria

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Shock Waves Reach Dental Implantology (Spanish)

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

StemWave vs. SoftWave: Which Shockwave Machine Should You Buy for Your Chiropractic Practice?

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

The Roll of Spark Waves in the Management of Chronic Wounds.

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Zimmer enPulsPro Shockwave Machines-

Shockwave Therapy for Chiropractors: Complete Guide

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

AUVA letter‒ Successful treatment of delayed and non-union fractures

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Acoustic Wave Therapy vs Shockwave Therapy

4 U. S. Patents issued on July 19, 2022

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Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

ESWT minimizes ischemic tissue necrosis…

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

What Is Li-ESWT & How Does It Work?

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

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Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Dr. Lohse Bush, first brain treatments

Mechano-transduction effect of shock waves

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Extracorporeal Shock Wave Therapy

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

10 Natural Ways to Find Pain Relief

Best Treatment for Tennis Elbow Relief

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Government Sales

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

EPAT Therapy for Plantar Fasciitis vs Alternatives

SoftWave vs Shockwave Technology Explained 

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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

SoftWave Therapy for Knees

SoftWave Therapy vs. Stem Wave & Acoustic Wave Devices for Knee Pain

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Current concepts of shockwave therapy in stress fractures

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Effects of ESWT on glycosaminoglycan expression during bone healing

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Set up Instructions

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Provider’s Guide to Shockwave Therapy for Wound Care

Provider’s Guide to Shockwave Therapy for Wound Care

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

7 Red Flags That Signal a Risky Shockwave Device

Can Shockwave Therapy Cause Damage?

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

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Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

​Extracorporeal shock wave therapy: What? Why? Safety?

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

ESWT for retracting scars of the hand

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Shockwave therapy in stress fractures

Is a Shockwave Therapy Machine for Home Use?

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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ISMST (International Society for Medical Shockwave Treatment)

Shock wave application to cell cultures

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Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

ESWT for resident stress fractures in athletes.

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Dr Irwin Goldstein Dinner Presentation – Nashville

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Shock waves induce angiogenesis via exosome release

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Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Heart Regeneration becomes Reality!

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Macrophage migration induces angiogenesis

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Shockwave Therapy Of The Heart​

Best Shockwave Machine for Providers

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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Treatment of stress urinary incontinence

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What Is a Focused Shockwave Therapy Machine?

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Expanding Non-Surgical Options in Podiatry Clinics

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

The Clinician’s Guide to Shockwave Therapy- Evidence, Safety, and Technology

The Clinician’s Guide to Shockwave Therapy: Evidence, Safety, and Technology

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

Biological mechanism of musculoskeletal shockwaves

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Mesenchymal stem cells: Myths and reality

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

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Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

ISSWSH Abstract

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Using Sound to Battle Opioid Crisis

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

How Li-ESWT Works for Patients With ED & Other Indications

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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Biological Principles – Mechanotransduction

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Optimization of screw fixation in rat bone with extracorporeal shock waves

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

The Applied Mechanical Vibration as Extracorporeal Shock Wave

How to Improve Podiatry Practice ROI

How to Improve Podiatry Practice ROI

Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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