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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

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Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

What Is Li-ESWT & How Does It Work?

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

ESWT minimizes ischemic tissue necrosis…

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Can You Use a Shockwave Therapy Machine at Home?

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Using acoustic therapy to prevent opioid addiction.

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Foot application

Shockwave Therapy for Podiatrists: A Complete Guide

Ultrasound Based Brain Stimulation

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal Magnetic Transduction Therapy Explained

Treatment for osteonecrosis of the femoral head

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

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Mesenchymal stem cells: Myths and reality

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

SoftWave TRT vs Storz Shockwave Machines Compared

Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

Biological mechanism of musculoskeletal shockwaves

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Technology Assessment “Wound Care” dermagold100

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Chattanooga Shockwave Devices Compared- What Clinicians Should Evaluate

Chattanooga Shockwave Therapy Devices Compared

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Shock wave therapy for osteoinduction

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

Scientific Reports – Gene transfection by shock waves

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Low Intensity Shockwave Therapy vs High Intensity: Which Works Best?

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

SoftWave Celebrates Pro Success of Golfer Jake Peacock and Baseball Player Reid Worley, Highlighting Injury Prevention Breakthroughs

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Equine extracorporeal shock wave therapy

Motor and Sensory Schwann Cell Phenotype

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Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

ISMST (International Society for Medical Shockwave Treatment)

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

​Antibacterial effects of extracorporeal shock waves

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

​Prospective randomized phase II trial of accelerated reepithelialization

Stem cells pose risk, offer promise

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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IVSWT Water Bath V2.0 Manual

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

EPAT Therapy for Plantar Fasciitis vs Alternatives

Latest Basic Research Abstracts

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

​Extracorporeal shock wave therapy: What? Why? Safety?

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Urological Times Cover – Scroll to Page 18 – 19

Traditional Reimbursement vs Hybrid Practice for Shockwave Providers

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Fully healed, Ordonez flourished for Tigers using ESWT

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Effect of shock waves on macrophages

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Mechano-transduction effect of shock waves

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Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

What Is Piezowave and How Does It Work?

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Treatment of scaphoid waist nonunion

Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Benefits of Spark Wave Therapy in neuronal regeneration

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Athletic therapy (Mts-Science)

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Angiogenic response upon shock wave treatment of the ischaemic muscle

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Erectile Dysfunction before and after results under ultrasound

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

SoftWave Therapy Averts Amputation for Former College Football Coach

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A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Extracorporeal shockwave therapy induces alveolar bone regeneration

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

MTS Science White Paper – Softwave – Pain Therapy

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Shockwave therapy in stress fractures

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Zimmer enPulsPro Shockwave Machines-

Shockwave Therapy for Chiropractors: Complete Guide

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Extracorporeal shock wave therapy for nonunion of the tibia

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Test43212

Piezowave Shockwave Therapy vs Other Shockwave Devices

Piezowave Shockwave Therapy vs Other Shockwave Devices

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Shock waves promote spinal cord repair via TLR32

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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Cellular mechanotransduction: putting all the pieces together again

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Shockwave Therapy for the Treatment of Cancer

Medispec Shockwave Devices- Efficacy & Alternatives

Medispec Shockwave Devices: Efficacy & Alternatives

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

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Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Shock wave treatment for in vitro engineering applications

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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