SoftWave Research

Newest Research

Sticky Post

SoftWave TRT Lands Prestigious VA Contract Revolutionizing Pain and Wound Management for Veterans

Amazon Healthcare veteran Chris Holt brings experience and a bold vision to lead SoftWave TRT's...
Read More
Sticky Post

Seven Trends in Healing for 2023

Smith, William The pace of innovation in regenerative medicine keeps getting faster. At clinics across...
Read More

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...
Read More

Technology Assessment “Wound Care” dermagold100

MTS-Science – ​Acute wounds are caused exogenously by traumatic (e.g. mechanical, chemical, thermical) or iatrogenic (e.g. surgical)...
Read More

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...
Read More

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

High energy diaphyseal fractures constitute a complicated matter for trauma units and urgent medical and...
Read More

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...
Read More

Angiogenic response upon shock wave treatment of the ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Tissue Regeneration Technologies – A four patient pilot trial was conducted in 2018 including four...
Read More

Motor and Sensory Schwann Cell Phenotype Commitment is Diminished by Extracorporeal Shockwave Treatment in vitro

The gold standard for peripheral nerve regeneration uses a sensory autograft to bridge a motor/sensory...
Read More

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Davis T, Stojadinovic A, Anam K, et al.Int Wound J. 2009; 6:11-21 Click here to read...
Read More

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

This RCT investigated the effect of non-invasive extracorporeal shockwaves on tooth mobility in orthodontic patients...
Read More

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Mayo Clinic – Extracorporeal shock wave therapy (ESWT) is a noninvasive treatment that involves delivery of shock...
Read More

Best Shockwave Therapy Machine For Providers

Extracorporeal shockwave therapy (ESWT) is a viable, growing treatment option for patients who are seeking...
Read More

Zapping chronic tendon pain

Click here to read more.
Read More

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment: A Systematic Review of the Literature

Robert Dymarek, PhD, PT; Tomasz Halski, PhD, PT; Kuba Ptaszkowski, PhD, PT; Lucyna Slupska, PhD,...
Read More

The Roll of Spark Waves in the Management of Chronic Wounds.

Antibiotic-resistant bacterial colonies often produce biofilms (a defensive mechanism that creates a physical protective barrier...
Read More

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Stojadinovic A, Elster E, Anam EA, et al.Angiogenesis. 2008; 11(4):369-380 Click here to read more.
Read More

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant...
Read More

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

A prospective, randomized, double‐blinded, controlled pilot trial of 24 abdominoplasty patients revealed that preoperative application...
Read More

Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

A. SKOLARIKOS, M.D., ALARGOF, M.D., RIGAS, M.D., DELIVELIOTIS, M.D. and E. KONSTANTINIDIS, M.D – To assess in...
Read More

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Patients with probable Alzheimer disease (AD) had sustained memory improvements months after ultrasound brain stimulation...
Read More

Successful treatment of nonunions with orthogold280

A pseudarthrosis is defined as a non healing fracture from which a false joint develops....
Read More

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

(Swiss Paraplegic Centre Nottwil) – Spasticity is the most problematic self-reported secondary medical problem in patients...
Read More

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...
Read More

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Hercher et al.TERMIS World Congress 2018 in Kyoto, Japan Click here to read more.
Read More

Benefits of Unfocused Li-ESWT for Erectile Dysfunction and Nocturia

When health issues arise, it is crucial to know what treatment options are available and...
Read More

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Thayná Melo de Lima Morais, Patrícia Froes Meyer, Liliane Santos de Vasconcellos, Julio Costa e Silva, Ito Ferreira e...
Read More

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Knowing the most effective treatment options for your patients is crucial for their speedy recovery....
Read More

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Professor Dr.-Ing. habil. Axel E. Theuer Click here to read more.
Read More

OrthoGold 100TM

Click here to read more.
Read More

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor...
Read More

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Rani S, Ritter T – Wound healing is a complex process and often delayed in patients with...
Read More

Treatment of stress urinary incontinence with low-intensity extracorporeal shock wave therapy in a vaginal balloon dilation induced rat model

To investigate the outcomes and mechanisms of low-intensity extracorporeal shock wave therapy (Li-ESWT) on stress...
Read More

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

van der Jagt OP, Piscaer TM, Schaden W, et al.J Bone Joint Surg Am. 2011; 93(2):38-48...
Read More

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Ottomann C., Antonic V., Münch S., et al.J Bioengineer & Biomedical Sci 2015, 6:12015 Click here...
Read More

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

Seventy-two patients with 72 chronic diabetic foot ulcers were randomly divided into two groups of...
Read More

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

(​Wei Wei, Hua-yu Tang, Yu-zhi Li, Tian-shu Wang) – : Previous clinical trials have reported that...
Read More

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Director Kompass Health Associates, Centre for Regenerative Health, Sports Performance & Research – Auckland, New...
Read More

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Rajendra Kashinath Shimpi, Ravi Jineshkumar Jain Department of Urology and Genito-Urinary Surgery, Ruby Hall Clinic,...
Read More

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

As new approaches for peripheral nerve regeneration are sought, there is an increasing demand for...
Read More

Shock wave therapy alone has no impact on cancer growth

Cancer remains one of the leading causes of morbidity and mortality throughout the world. Several...
Read More

Scientific Reports – Gene transfection by shock waves

Extracorporeal shock wave (SW) therapy has been studied in the transfection of naked nucleic acids...
Read More

Principles of Shock Wave Therapy

John A. Ogden, MD; Anna Tóth-Kischkat, PhD; and Reiner Schultheiss, PhD Click here to read...
Read More

Spark Wave® Therapy Ameliorates Urinary Incontinence

MTS-Science April 14th, 2019. Stress urinary incontinence (SUI) is the involuntary leakage of urine during activities such...
Read More

MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science​  – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and...
Read More

Alternatives to Cortisone Shots

If you have a patient with debilitating joint pain, you may have recommended or administered...
Read More

Sound Frequency Healing: The Spark of Life

By: Dr. Matt DiDuro How Sound Frequency Healing Works SoftWave’s sound frequency healing technology, known...
Read More

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

The objective of this study is to demonstrate the efficacy and safety of AWT(®), combining two different mechanical...
Read More

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Graber et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
Read More

The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...
Read More

Extracorporeal shock wave therapy for nonunion of the tibia

Delayed and nonunion of the tibia are not uncommon in orthopedic practice. Multiple methods of...
Read More

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...
Read More

How Shockwave Therapy Breaks Down Scar Tissue

The benefits of Extracorporeal Shock Wave Therapy (ESWT) when used to treat chronic and acute...
Read More

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

We tested whether shock wave (SW) offers additional benefits in improving left ventricular (LV) function...
Read More

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Department of Urology, Eastern Virginia Medical School, Norfolk, VA, *Division of Urologic Surgery, University of...
Read More

Influence of medical shock waves on healthy muscle tissue

Competitive sport requires each athlete to be at peak performance at all times. This is...
Read More

Alternative Treatment for Erectile Dysfunction with the Urogold 100™

MTS Science Published on Jun 21, 2016 – The improvement of Erectile Dysfunction through the treatment with...
Read More

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

The use of non-invasive brain therapies has become a hot topic recently. Alzheimer’s and Parkinson’s...
Read More

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

(Shih-Feng Lin, Yi-Jen Chen, Hung-Pin Tu , Chia-Ling Lee, Ching-Lin Hsieh , Wen-Lan Wu ,...
Read More

ISSWSH Abstract

Click here to read more.
Read More

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

Shockwave therapy was originally developed to disintegrate urinary stones 4 decades ago1 . Since then,...
Read More

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Human bone marrow stromal cells (hBMSCs) bear tremendous clinical potential due to their immunomodulatory properties...
Read More

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice,...
Read More

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

(Tz-Yan Lin, Jing-Ting Chen, Yu-Yu Chen, Tien-Wen Chen , Chia-Ling Lee, Chia-Hsin Chen, Mao-Hsiung Huang)...
Read More

SoftWave Tissue Regeneration Technologies Receives Innovative Technology Contract from Vizient For DermaGold®

SoftWave Tissue Regeneration Technologies announced its DermaGold,® an advanced wound care technology, has received an...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...
Read More

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Alessandro Palmieri, Ciro Imbimbo, Nicola Longo, Ferdinando Fusco, Paolo Verze, Francesco Mangiapia, Massimiliano Creta ,...
Read More

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Currently, there are no effective therapy strategies for idiopathic, non-organic vulvodynia in women. ESWT (extracorporeal...
Read More

Shock Waves Reach Dental Implantology (Spanish)

Lithotripsy or Shock Wave Therapy is proving to be an effective non-invasive treatment to regenerate...
Read More

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

(Yousef Marwan, MBBS, Wael Husain, MBBS, FRCSC , Waleed Alhajii, MBBS, MSc, Facharztb , Magdy...
Read More

Reduce Inflammation Naturally With Shockwave Therapy

Like all things, inflammation is good and healthy in moderation, but when it becomes chronic,...
Read More

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD, Bernd Hartmann, MD, Josh Tyler, MD, Heike Maier, MD, Richard Thiele, MD,Wolfgang...
Read More

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Liver cirrhosis is a life-threatening problem; a considerable proportion of patients with liver cirrhosis progress...
Read More

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Van der Jagt et al.Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society,...
Read More

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

 (Georgia Urology, Atlanta, USA. 2018) Testosterone in males is produced in the testicles. With aging...
Read More

Chris Holt Takes the Helm as New CEO of SoftWave Tissue Regeneration Technologies, Ushering in a New Era of Growth

Amazon Healthcare veteran Chris Holt brings experience and a bold vision to lead SoftWave TRT's...
Read More

Shockwave Therapy for Calcific Tendonitis

Shoulder pain is a prevalent complaint that affects millions of individuals worldwide. In fact, it’s...
Read More

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...
Read More

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Ultrasound based brain stimulation techniques may become a powerful new technique to modulate the human...
Read More

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...
Read More

Benefits of Spark Wave Therapy in neuronal regeneration

(MTS Science) – Extracorporeal shock wave therapy (ESWT) is widely used in clinical practice. In addition to...
Read More

Ultrasound Based Brain Stimulation

Ultrasound based brain stimulation techniques bay become a powerful new technique to modulate the human...
Read More

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...
Read More

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Van der Jagt et al.Journal of Orthopaedic Research, 31(5), 768–775. https://doi.org/10.1002/jor.22258. Click here to read more.
Read More

TRT SoftWaves® – a new regenerative therapy for paraplegia

Extracorporeal softwave therapy (ESWT) is widely used in clinical practice. In addition to its original...
Read More

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Erectile dysfunction is highly prevalent in type II diabetes mellitus.Low intensity extracorporeal shock wave therapy...
Read More

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...
Read More

Set up Instructions

Video for setting up the device, inserting the applicator and water cartridge, and how to...
Read More

Molecular changes in diabetics foot ulcers

The Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College...
Read More

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Holfeld et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
Read More

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The...
Read More

The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria;  AUVA Trauma Center Meidling, Vienna, Austria; ...
Read More

The Best Alternatives to Rotator Cuff Surgery

Rotator cuff injuries are all-too-frequent in the United States, affecting millions of people throughout the...
Read More

Optimization of screw fixation in rat bone with extracorporeal shock waves

Koolen et al.Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23615. Click here to read more.
Read More

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Since December, 2019, an outbreak of pneumonia caused by a novel coronavirus (SARS-CoV-2) has raised...
Read More

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

A Systematic Scoping Review of Pre-Clinical Studies – Using Cochrane’s methodologic recommendations on scoping studies and...
Read More

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Schaden W, Mittermayr R.Jatros Orthopädie & Rheumatologie. 5/2011; 72-74 Click here to read more.
Read More

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Extracorporeal shock wave therapy (ESWT) uses acoustic pulses to treat certain musculoskeletal disorders. In this...
Read More

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Hexsel D, Camozzato FO, Silva AF, Siega Cellulite is a commonality among most women and some men. As...
Read More

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Angiotensin-converting enzyme (ACE2) has a multiplicity of physiological roles that revolve around its trivalent function:...
Read More

4 U. S. Patents issued on July 19, 2022

SoftWave officially has been granted 4 new patents as of July 19, 200. They include...
Read More

Equine extracorporeal shock wave therapy

Extracorporeal shock wave therapy (ESWT) is an accepted form of treatment for chronic cases of...
Read More

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue...
Read More

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis,...
Read More

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Dental implants are a routine procedure within the therapeutic range of dentists. Many loading protocols...
Read More

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Nägele et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
Read More

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, inflammatory response leading...
Read More

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Thomas A Davis, Alexander Stojadinovic, Khairul Anam, Mihret Amare, Shruti Naik, George E Peoples, Douglas...
Read More

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Breast cancer diagnosis and treatment with sentinel lymph node biopsy, axillary lymph node dissection and...
Read More

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Carlotta Scarpa, MD, PhD, Vincenzo Vindigni, MD, PhD, and Franco Bassetto, MD Acoustic waves are mechanical waves...
Read More

Stemwave Therapy

What is Stemwave Therapy? Stemwave therapy is a commonly used term that can be synonymous...
Read More

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...
Read More

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...
Read More

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt Department of General...
Read More

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Fuchs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
Read More

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...
Read More

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

SoftWave® Tissue Regeneration Technologies, a disruptive bio-medical device company, announces the beginning of a trial...
Read More

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Cellulite is a multifactorial condition that is present in 80-90 % of post-pubertal women, commonly found...
Read More

Shock wave therapy for osteoinduction

Koolen et al. 20th ISMST Congress in San Sebastian, Spain Abstract P33 Click here to...
Read More

The effect of shock waves on in vitro cartilage development in silk scaffolds

Szwarc et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
Read More

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...
Read More

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Extracorporeal shockwave therapy (ESWT) is used in a number of indications in the medical field....
Read More

Effectiveness of Extracorporeal Shock Wave Lithotripsy to treat Dystrophic Calcinosis Cutis

Delgado-Marquez et al.Actas Dermosifiliogr. 2015 Mar;106(2):140-3. doi: 10.1016/j.ad.2014.06.006.  Click here to read more.
Read More

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

PRESS RELEASE PR Newswire 2018 – Comprehensive Urology Medical Group, one of the nation’s leading...
Read More

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Scaphoid nonunion remains challenging for hand surgeons. Several treatment options are available such as: non-vascularized or...
Read More

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

A novel coronavirus (2019-nCoV) was identified as the cause associated with emerging pneumonia (COVID-19) detected...
Read More

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Tepeöylü et al.Journal of Tissue Engineering and Regenerative Medicine, 12(1), e486–e494. https://doi.org/10.1002/term.2317.2018 Click here to read...
Read More

Biological mechanism of shockwave in bone

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through...
Read More

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and...
Read More

Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...
Read More

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Priglinger et al.Cytotherapy. 2017 Sep;19(9):1079-1095. doi: 10.1016/j.jcyt.2017.05.010. Epub 2017 July 19, 2017 Click here to read...
Read More

Urological Times Cover – Scroll to Page 18 – 19

Urological Times – It’s hard to argue against an erectile dysfunction treatment that is potentially...
Read More

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...
Read More

SoftWave TRT Selected to Exhibit DermaGold at Vizient Innovative Technology Exchange

Amazon Healthcare veteran Chris Holt brings experience and a bold vision to lead SoftWave TRT's...
Read More

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...
Read More

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal...
Read More

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

Postischemic cardiomyopathy remains one of the disorders in urgent need of effective noninvasive therapy. It...
Read More

ESWT for resident stress fractures in athletes.

Stress fractures are major concerns with athletes. It is sometimes difficult to repair, resulting in...
Read More

Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...
Read More

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Research Institute of Environmental Medicine at Heinrich-Heine University, D-40021 Duesseldorf,Germany In vivo measurements in 26...
Read More

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

(Yousef Marwan, • Bashar Dahrab • Ali Esmaeel • Samir Abdulrazik Ibrahim • Jassim Al-Failakawi)...
Read More

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Holfeld et al. 20th ISMST Congress in San Sebastian, Spain Abstract P30 Click here to...
Read More

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

Extracorporeal shock wave therapy has been used in various clinical conditions as a result of...
Read More

Shockwave Therapy for Achilles Tendonitis

Achilles tendonitis is a common condition that causes pain and swelling in the Achilles tendon,...
Read More

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process...
Read More

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

IRB study at Georgia Urology, Atlanta, USA – Since 2007 at least 250.000 ED patients have...
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Effects of ESWT on glycosaminoglycan expression during bone healing

Several cases of delayed bone consolidation have been treated with extracorporeal shock wave therapy (ESWT) to improve bone...
Read More

​Exosomes and Cardiovascular Protection

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called...
Read More

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

Background-—Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular...
Read More

Penile low intensity shock wave therapy for PDE5i non responders: A prospective, randomized, placebo-controlled study

Fundació Puigvert, Barcelona, Spain European Congress of Andrology, Rotterdam, Netherlands Click here to read more.
Read More

Novel Approach to Obtain an Activated Fat Graph

One of the mainstays of facial rejuvenation strategies is volume restoration, which can be achieved...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

ESWT for Acute and Chronic Soft Tissue Wounds

Wolfgang Schaden, M.D., Richard Thiele, M.D., Christine Kölpl, M.D., Michael Pusch, M.D., Aviram Nissan, M.D.,...
Read More

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as...
Read More

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...
Read More

SoftWave TRT Leads the Charge: Secures CPT Code Approval for Groundbreaking men’s sexual health and Shockwave Therapy

Amazon Healthcare veteran Chris Holt brings experience and a bold vision to lead SoftWave TRT's...
Read More

Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

MTS Science – Low Intensity Shock Wave (LiSW) has emerged as a therapy for vasculogenic erectile...
Read More

Biologic Response

LL37 and shock waves

Click here to read more.
Read More

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Shockwave treatment enhances cell proliferation and improves wound healing by ATP release coupled extracellular signal-regulated kinase (ERK) activation

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
Read More

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
Read More

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
Read More