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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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​Prospective randomized phase II trial of accelerated reepithelialization

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Extracorporeal Shock Wave Therapy: Current Evidence

Shock wave treatment for in vitro engineering applications

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Equine extracorporeal shock wave therapy

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Shock wave treatment enhances stemness and preserves multipotency

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

SoftWave TRT vs Storz Shockwave Machines Compared

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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What Doctors Should Know About Storz Medical Shockwave

The Best Alternatives to Rotator Cuff Surgery

Alternatives to Rotator Cuff Surgery

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Physical Rehabilitation Using Shockwave Therapy

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Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Scientific Reports – Gene transfection by shock waves

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Using acoustic therapy to prevent opioid addiction.

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Principles of Shock Wave Therapy

Mesenchymal stem cells: Myths and reality

Motor and Sensory Schwann Cell Phenotype

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The influence of comorbidities – ESWT for chronic soft tissue wounds

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave Therapy for Acute vs Chronic Wound Treatment

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What are the Side Effects of SoftWave Therapy

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Medispec Shockwave Devices- Efficacy & Alternatives

Medispec Shockwave Devices: Efficacy & Alternatives

ESWT for Acute and Chronic Soft Tissue Wounds

Dr. Lohse Bush, first brain treatments

Ultrasound Based Brain Stimulation

Optimization of screw fixation in rat bone with extracorporeal shock waves

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Influence of medical shock waves on healthy muscle tissue

Zimmer enPulsPro Shockwave Machines-

Shockwave Therapy for Chiropractors: Complete Guide

What Is Piezowave and How Does It Work?

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Set up Instructions

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OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Heart Regeneration becomes Reality!

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Expanding Non-Surgical Options in Podiatry Clinics

Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave vs Shockwave Technology Explained 

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SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Effect of shock waves on macrophages

​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

Spark Wave® Therapy Improves Full Thickness Skin Defects

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

ESWT in skin & aesthetic indications

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Extracorporeal Magnetic Transduction Therapy Explained

EMTT vs. Shockwave Therapy: A Clinical Comparison for Providers

Effect of shockwave therapy on orthodontic tooth movement

Mechano-transduction effect of shock waves

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Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Shockwave treatment enhances cell proliferation and improves wound healing

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Traditional Reimbursement vs Hybrid Practice for Shockwave Providers

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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Best Shockwave Machine for Providers

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Biological mechanism of musculoskeletal shockwaves

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Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Shockwave Therapy vs. Ultrasound Therapy

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

The effect of shock waves on in vitro cartilage development in silk scaffolds

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Technology Assessment “Wound Care” dermagold100

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Shock wave therapy for systemic sclerosis

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7 Red Flags That Signal a Risky Shockwave Device

Can Shockwave Therapy Cause Damage?

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Extracorporeal shock waves, a new non-surgical method to treat severe burns

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

EPAT Therapy Costs for Patients & Practices

Government Sales

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

How Li-ESWT Works for Patients With ED & Other Indications

Gainswave Machines: Cost, Efficacy, & Alternatives

SoftWave vs. GainsWave Therapy for ED and Beyond

Shock wave therapy for osteoinduction

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Molecular changes in diabetics foot ulcers

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

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Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

MTS Spark Wave Publications – Science Telegram

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Piezowave Shockwave Therapy vs Other Shockwave Devices

Piezowave Shockwave Therapy vs Other Shockwave Devices

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

10 Natural Ways to Find Pain Relief

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

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A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

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A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Spark Wave® Therapy Ameliorates Urinary Incontinence

ISSWSH Abstract

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Is surgery the only option for bone-on-bone?

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Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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Shockwave Therapy Helping Patients With Peripheral Artery Disease

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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DolorClast Therapy- Mechanism, Indications, and Clinical Evidence

DolorClast Therapy: What Is It & Does It Work for Patients?

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Treatment of stress urinary incontinence

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Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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