SoftWave Research

Newest Research

In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells

Schuh et al.Cytotherapy, 16(12), 1666–1678. https://doi.org/10.1016/j.jcyt.2014.07.005. Click here to read more.

The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

She was treated with high dose antibiotics. Surgeons recommended a colostomy and several operations to...

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Sansone V, D’Agostino MC, Bonora C, et al.Journal of Biological Regulators & Homeostatic Agents 2012; 26(1):29-37...

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement – a randomized clinical trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice,...

Analysis of treatment protocols: application of ESWT for wound healing disorders

Shock waves are high-energy acoustic waves characterized by an initial rise of high pressure within...

Spark Wave® Therapy Improves Cardiac Function

Ischemic heart disease remains the leading cause of mortality (12.7%) worldwide, causing more than 7...

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Zins et al.Angiogenesis, 13(4), 293–304. https://doi.org/10.1007/s10456-010-9186-9. Click here to read more.

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

We prospectively studied extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder in...

Mesenchymal stem cells: Myths and reality

Mesenchymal stem cells (MSCs; also called mesenchymal stromal cells) have received much attention during the...

Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Rajendra Kashinath Shimpi, Ravi Jineshkumar Jain Department of Urology and Genito-Urinary Surgery, Ruby Hall Clinic,...

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Maria Cristina D’Agostino, Simona Maria Carmignano, and Andrea Saggini Click here to read more.

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...

Indications for shockwaves in veterinary medicine

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The biologic effects of SoftWaves and rationale for spine and brain therapy

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Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Rainer Mittermayr, MD; Vlado Antonic, MS; Joachim Hartinger ; Hanna Kaufmann, MD ; Heinz Redl,...

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

This RCT investigated the effect of non-invasive extracorporeal shockwaves on tooth mobility in orthodontic patients...

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

High energy diaphyseal fractures constitute a complicated matter for trauma units and urgent medical and...

Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...

Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

American Urological Association 2017 – American Urological Association. Dr. Tom Lue addressing erectile dysfunction during...

Impact of extracorporeal shockwave therapy on tooth mobility in adult orthodontic patients: a randomized single-center placebo-controlled clinical trial

Falkensammer et al.J Clin Periodontol. 2015 Mar;42(3):294-301. doi: 10.1111/jcpe.12373. Epub Click here to read more.

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

Powerpoint abstract. Click here to read more.

Extracorporeal shock wave therapy in periodontics: A new paradigm

The quest for exploring new frontiers in the field of medical science for efficient and...

Current concepts of shockwave therapy in stress fractures

Stress fractures are common painful conditions in athletes, usually associated to biomechanical overloads. Low risk...

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

Lobenwein D., Tepeköylü C., et al.J Am Heart Assoc. 2015 Oct 27;4(10):e0024402015 Click here to read...

Zapping chronic tendon pain

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Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal...

The effect of shock waves on in vitro cartilage development in silk scaffolds

Szwarc et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Feichtinger et al.Am J Sports Med. 2019 Jul;47(9):2158-2166.2019 Click here to read more.

Shock wave application to cell cultures

Holfeld J., Tepeköylü C., et al.J Vis Exp. 2014 Apr 8;(86).2014 Click here to read...

Heart Regeneration becomes Reality!

Regeneration of infarcted heart muscle remained a dream of modern medicine despite of comprehensive research...

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Thomas A Davis, Alexander Stojadinovic, Khairul Anam, Mihret Amare, Shruti Naik, George E Peoples, Douglas...

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...

Prophylactic low-energy shock wave therapy improves wound healing after vein harvesting for coronary artery bypass graft surgery: A prospective, randomized trial

Dumfarth J, Zimpfer D, Vögele-Kadletz, et al.Ann Thorac Surg. 2008; 86:1909-13 Click here to read more.

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process...

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Focused extracorporeal shockwave therapy (ESWT) has been demonstrated to improve wound healing and skin regeneration such as in burn...

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Graber et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Larking AM, Duport S, Clinton M, et al.Clin Rehabil. 2010; 24(3):222-9 Click here to read more.

Shock Waves Reach Dental Implantology (Spanish)

Lithotripsy or Shock Wave Therapy is proving to be an effective non-invasive treatment to regenerate...

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

Low energy shock waves have been shown to induce angiogenesis, improve left ventricular ejection fraction...

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Hazan-Molina H., Reznick AZ., Kaufman H., Aizenbud D.Arch Oral Biol. 2013 Feb;58(2):142-50. Click here to read...

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Alessandro Palmieri, Ciro Imbimbo, Nicola Longo, Ferdinando Fusco, Paolo Verze, Francesco Mangiapia, Massimiliano Creta ,...

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

Shockwave therapy was originally developed to disintegrate urinary stones 4 decades ago1 . Since then,...

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Peyronie’s Disease (PD), and Sexual Rehabilitation After Radical Prostatectomy With Special Focus on Technical Aspects...

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Department of Rehabilitation Medicine, Nan Lou of Chinese PLA General Hospital, Beijing, China – This study...

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

MTS-Science Low-intensity extracorporeal shock wave therapy (LI-ESWT) is of great clinical interest for the treatment...

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

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Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

In this prospective design study the effects of low-energy partially focusedextracorporeal generated shock waves (ESW)...

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Hercher et al.TERMIS World Congress 2018 in Kyoto, Japan Click here to read more.

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

(Yousef Marwan, • Bashar Dahrab • Ali Esmaeel • Samir Abdulrazik Ibrahim • Jassim Al-Failakawi)...

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

(Shih-Feng Lin, Yi-Jen Chen, Hung-Pin Tu , Chia-Ling Lee, Ching-Lin Hsieh , Wen-Lan Wu ,...

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy.

Quadlbauer et al.Arch Orthop Trauma Surg. 2019 Feb;139(2):281-293.2019 Click here to read more.

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shock-wave (ESW) treatment has been shown to be effective in promoting the healing of...

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Currently, there are no effective therapy strategies for idiopathic, non-organic vulvodynia in women. ESWT (extracorporeal...

Prospective randomized phase II trial of accelerated reepithelialization

Christian Ottomann, MD, Alexander Stojadinovic, MD, FACS, Philip T. Lavin, PhD,§ Francis H. Gannon, MD,...

Treatment of stress urinary incontinence with low-intensity extracorporeal shock wave therapy in a vaginal balloon dilation induced rat model

To investigate the outcomes and mechanisms of low-intensity extracorporeal shock wave therapy (Li-ESWT) on stress...

STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new...

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Erectile dysfunction is highly prevalent in type II diabetes mellitus.Low intensity extracorporeal shock wave therapy...

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

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Shock waves promote spinal cord repair via TLR32

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Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

Shock waves have been shown to induce recruitment of intravenously injected endothelial progenitor cells to...

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Effect of shockwave therapy on orthodontic tooth movement

ESWT delays orthodontic tooth movement in rats and promotes osteoblast and osteoclast differentiation. Click here...

Case Series of Weekly Low Intensity Shockwave Therapy for Erectile Dysfunction

Shoskes et al., Cleveland Clinic, United States 20th ISMST Congress in San Sebastian, Spain Abstract...

Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

Periodontal inflammation with alveolar bone resorption is a hallmark of periodontitis. We hypothesized that extracorporeal...

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

IRB study at Georgia Urology, Atlanta, USA – Since 2007 at least 250.000 ED patients have...

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...

AUVA letter‒ Successful treatment of delayed and non-union fractures

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Effects of low-energy shock waves on oral bacteria

Novak KF, Govindaswami M, Ebersole JL et al.J Dent Res. 2008 Oct;87(10):928-31 Click here to read...

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Van der Jagt et al.Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society,...

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Liver cirrhosis is a life-threatening problem; a considerable proportion of patients with liver cirrhosis progress...

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Journal of Sexual Medicine (Guiting Lin MD PhD, Amanda B. Reed-Maldonado MD, Bohan Wang MD,...

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: effects of extracorporeal shock wave therapy

Zins SR., Amare MF., et al.Angiogenesis. 2010 Dec;13(4):293-304. Click here to read more.

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Paul Slezak ISMST 2017 San Sebastian Click here to read more.

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis,...

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but...

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

The objective of this study was to determine the safety and efficacy of noninvasive lipolysis of excess adiposities overlying the lateral...

Shockwaves prevent from heart failure after acute myocardial ischaemia via RNA/protein complexes

Tepeöylü et al.J Cell Mol Med. 2017 Apr;21(4):791-801. doi: 10.1111/jcmm.13021.2017 Click here to read more.

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Scaphoid nonunion remains challenging for hand surgeons. Several treatment options are available such as: non-vascularized or...

Development of a prognostic naïve Bayesian classifier for successful treatment of nonunions

Stojadinovic A, Kyle Potter B, Eberhardt J, et al.J Bone Joint Surg Am. 2011; 93:187-194 Click...

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag)

A prospective, randomized, double‐blinded, controlled pilot trial of 24 abdominoplasty patients revealed that preoperative application...

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Thayná Melo de Lima Morais, Patrícia Froes Meyer, Liliane Santos de Vasconcellos, Julio Costa e Silva, Ito Ferreira e...

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a form of energy transfer that is of...

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Research Institute of Environmental Medicine at Heinrich-Heine University, D-40021 Duesseldorf,Germany In vivo measurements in 26...

Biological mechanism of shockwave in bone

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through...

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

The purpose of this meta-analysis was to assess the effects of extracorporeal shock wave therapy...

Shock wave treatment protects from neuronal degeneration via a toll-like receptor 3 dependent mechanism: implications of a first-ever causal treatment for ischemic spinal cord injury

(Daniela Lobenwein, MD; Can Tepek€oyl€u, MD; Radoslaw Kozaryn, MD; Elisabeth J. Pechriggl, MD; Mario Bitsche,...

Extracorporeal shockwave therapy for treatment of keloid scars

Center for Shockwave Medicine and Tissue Engineering, Department of Orthopedic Surgery/Sports Medicine, Kaohsiung Chang Gung...

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Onger et al.Med Oral Patol Oral Cir Bucal. 2017 Mar 1;22(2):e251-e257.2017 Click here to read...

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

Extracorporeal softwave treatment is CE certified in Austria, Europe and licensed for indications like achillodynia,...

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Jieyuan Zhang, Junjie Guan, Xin Niu, Guowen Hu, Shangchun Guo , Qing Li , Zongping...

Efficacy of Unfocused Medium-Intensity Extracorporeal Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Extracorporeal shock wave therapy (ESWT) is a promising treatment for plantar fasciitis (PF), however, treatment...

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Patients with systemic sclerosis (SSc) often display Raynaud’s phenomenon and digital skin ulcers. As these...

Shockwave Therapy Differentially Stimulates Endothelial Cells: Implications on the Control of Inflammation via Toll-Like Receptor 3

Holfeld J., Tepeköylü C,. et al.Inflammation.2013 Feb; 37(1):65-70 Click here to read more.

ESWT minimizes ischemic tissue necrosis…

Rainer Mittermayr, MD, Joachim Hartinger, Vlado Antonic, MS, Alexandra Meinl, PhD, Sabine Pfeifer, Alexander Stojadinovic,...

Antibacterial effects of extracorporeal shock waves

Klinik und Poliklinik für Orthopädie und Sportorthopädie der Technischen Universität München, München, Germany; and Institut...

Effects of Low-Energy Shock Waves on Oral Bacteria

The objective of the present study was to determine any antibacterial effect of ESWT on...

ISSWSH Abstract

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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Holfeld J., Tepeköylü., et al.Cardiovasc Res. 2016 Feb 1;109(2):331-43. Click here to read more.

Shock wave treatment protects from neuronal degeneration via a toll-like receptor 3 dependent mechanism: implications of a first-ever causal treatment for ischemic spinal cord injury

Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular...

Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

From Henry M. Jackson Foundation for Advancement in Military Medicine, Rockville, MD; Combat Wound Initiative...

FDA Devices and Indications

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Extracorporeal Shock Wave Device for Treatment of Chronic Burns

486421907-fda-chronic-wounds-burns

The link between shockwaves and innate immunity – the main working mechanism?

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Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Grzegorz Lukasz Fojeck · Stefan Tiessen · Palle Jörn Sloth Osther 2017 – The objective was...

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as...

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Anna M Larking, Sophie Duport Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, Michael Clinton...

CLEARANCES

Lithotriptor, Extracorporeal Shock-Wave, Urological – LithoGoldMassager, Therapeutic, Electric – DermaGold; OrthoGold; UroGoldMassager, Therapeutic, Electric –...

Acoustic Field of a Ballistic Shock Wave Therapy Device

Abstract—Shock wave therapy (SWT) refers to the use of focused shock waves for treatment of...

SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

Prof. Hilde Beele (MD), Steven Smet, Francis Ramboer, at Ghent University Hospital faced up to the great...

Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant...

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

The authors of several studies have recommended extracorporeal shock-wave therapy as an alternative to surgical...

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into...

Stem cells pose risk, offer promise

Providing the therapy involves using an FDA cleared device with “genuine” shock waves, according to...

MTS Spark Wave Publications – Science Telegram

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Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

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Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

Background-—Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular...

Effects of low-energy shockwave therapy on the erectile function and tissue of a diabetic rat model

Qui et al.The Journal of Sexual Medicine, 10(3), 738–46. https://doi.org/10.1111/jsm.12024. Click here to read more.

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

Holfeld J.,Tepeköylü C., Blunder S., et al.PLoS One. 2014 Aug 5;9(8):e1039822014 Click here to read more.

Effectiveness of Extracorporeal Shock Wave Lithotripsy to treat Dystrophic Calcinosis Cutis

Delgado-Marquez et al.Actas Dermosifiliogr. 2015 Mar;106(2):140-3. doi: 10.1016/j.ad.2014.06.006. Click here to read more.

ESWT for resident stress fractures in athletes.

Stress fractures are major concerns with athletes. It is sometimes difficult to repair, resulting in...

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The...

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

(AUVA Research Center, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology,Vienna, Austria, 2 Austrian Cluster...

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

The current ‘‘gold standard’’ for treatment of chronic fracture nonunion in the metaphyseal-diaphyseal region of...

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

Tepeköylü C., Lobenwein D., Blunder S., et al.Eur J Cardiothorac Surg. 2015 Mar;47(3):e80-90. Click here to...

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous...

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....

ESWT in skin & aesthetic indications

ESWT in skin graft epithelialization 3 days faster healing. Click here to read more.

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells

Rohringer et al. PLoS ONE, 9(12). https://doi.org/10.1371/journal.pone.0114806. Click here to read more.

STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new...

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Holfeld et al. 20th ISMST Congress in San Sebastian, Spain Abstract P30 Click here to...

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

2016 Dietz-Laursonn Click here to read more.

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Karsten Knobloch • Beatrice Joest • Robert Kra ̈mer • Peter M. Vogt – Focused extracorporeal shockwave...

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, inflammatory response leading...

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Extracorporeal shock wave therapy (ESWT) uses acoustic pulses to treat certain musculoskeletal disorders. In this...

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Cell-based therapies with autologous adipose tissue–derived cells have shown great potential in several clinical studies...

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

For almost 30 years, extracorporeal shock wave therapy has been clinically implemented as an effective...

Dr. Lohse Bush, first brain treatments

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Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

In a prospective clinical trial, ESWT was performed consecutively 4 times over two weeks in...

Motor and sensory Schwann cell phenotype commitment is diminished by extracorporeal shockwave treatment in vitro

Spark Wave® helps the regeneration of nerve cells! This is the result of a new...

Shock waves promote spinal cord repair via TLR3

Spinal cord injury (SCI) remains a devastating condition with poor prognosis and very limited treatment...

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

(Notarnicola, Maccagnano, Gallone, Mastromauro, Rifino, Pesce, Covelli , Moretti B) The physiotherapy treatment of low...

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Schaden W, Mittermayr R.Jatros Orthopädie & Rheumatologie. 5/2011; 72-74 Click here to read more.

Shockwave therapy in stress fractures

Stress fractures are common painful conditions in athletes, usually associated to biomechanical overloads. Low risk stress...

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

Inflammatory processes play an important role in post-infarction myocardial remodelling. Adequate repair after loss of...

Shock wave therapy for systemic sclerosis

We studied the effects of ESWT in 8 SSc female patients who received 4 consecutive...

Extracorporeal shock wave therapy induces alveolar bone regeneration

Periodontal inflammation with alveolar bone resorption is a hallmark of periodontitis. We hypothesized that extracorporeal...

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, inflammatory response leading...

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

MTS Science 2016. Urogenital indications such as painful penile angulation, erection problems and / or chronic...

Extracorporeal shock wave therapy: clinical applications and regulation

Shock wave therapy is a relatively new modality for use in equine practice. The application...

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Extracorporeal Shock Wave Research Unit, Department of Anatomy II, Ludwig-Maximilians-University of Munich, Pettenkoferstr. Extracorporeal shock wave...

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

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SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

ATLANTA, May 19, 2021 (Newswire) – SoftWave Tissue Regeneration Technologies patented extracorporeal shock wave device called...

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Treatment for osteonecrosis of the femoral head: comparison of extracorporeal shock waves with core decompression and bone-grafting

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Shock wave treatment for in vitro engineering applications

Weihs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Fully healed, Ordonez flourished for Tigers using ESWT

To fix an ailing knee that would not heal because blood had stopped circulating to...

Penile low intensity shock wave therapy for PDE5i non responders: A prospective, randomized, placebo-controlled study

Fundació Puigvert, Barcelona, Spain European Congress of Andrology, Rotterdam, Netherlands Click here to read more.

Macrophage migration induces angiogenesis in ischemic myocardium after direct epicardial shock wave treatment

Holfeld et al. Thorac. Cardiovasc. Surg. (2012). doi:10.1055/s-0031-1297858 Click here to read more.

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Davis T, Stojadinovic A, Anam K, et al.Int Wound J. 2009; 6:11-21 Click here to read...

Ultrasound Based Brain Stimulation

Ultrasound based brain stimulation techniques bay become a powerful new technique to modulate the human...

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...

MTS Science White Paper – Softwave – Pain Therapy

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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Since December, 2019, an outbreak of pneumonia caused by a novel coronavirus (SARS-CoV-2) has raised...

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis

The goal for treating osteoarthritis (OA) is finding ways to decrease joint pain and dysfunction...

Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Human bone marrow stromal cells (hBMSCs) bear tremendous clinical potential due to their immunomodulatory properties...

Shock waves induce angiogenesis via exosome release

Graber et al. 20th ISMST Congress in San Sebastian, Spain Abstract P25 Click here to...

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

CREST syndrome is a variant of systemic sclerosis, which affects a relatively small number of...

Prospective randomized phase II trial of accelerated reepithelialization of superficial second-degree burn wounds using extracorporeal shock wave therapy

Ottomann C, Stojadinovic A, Lavin P, et al.Ann Surg. 2012; 255(1):23-9 Click here to read more.

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Yard DH.Renal & Urology News. 2011 Click here to read more.

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Platelet-rich plasma (PRP) and extracorporeal shockwave therapy (ESWT) are both used for the treatment of...

Athletic therapy (Mts-Science)

In modern society today, sport activity is becoming increasingly important. Reasons include more free time,...

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Department of Plastic, Aesthetic and Reconstructive Surgery and Burn Center Vall d’Hebron University Hospital, Autonomous...

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Schuh et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy

As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous...

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

Wound healing disorders after vein harvesting for coronary artery bypass graft surgery increase morbidity and...

Extracorporeal shockwave treatment impedes tooth movement in rats

Accelerated tooth movement has been a topic of interest for orthodontic research recently. Surgically facilitated...

Extracorporeal shock wave therapy: What? Why? Safety?

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Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Ottomann C, Hartmann B, Tyler j, et al.J Am Coll Surg. 2010; 211(3):361-7 Click here to...

Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

The main aim of our research in this field is to regenerate infarcted myocardium, respectively...

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

Extracorporeal shock wave therapy has been used in various clinical conditions as a result of...

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