SoftWave Research

Newest Research

Extracorporeal Shockwave Therapy Versus Ultrasound Therapy for Plantar Fasciitis

Systematic Review and Meta-Analysis – Objective To compare the outcomes of Extracorporeal Shockwave Therapy (ESWT) versus...
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Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Yard DH.Renal & Urology News. 2011 Click here to read more.
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A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Alessandro Palmieri, Ciro Imbimbo, Nicola Longo, Ferdinando Fusco, Paolo Verze, Francesco Mangiapia, Massimiliano Creta ,...
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Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD, Bernd Hartmann, MD, Josh Tyler, MD, Heike Maier, MD, Richard Thiele, MD,Wolfgang...
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Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Davis T, Stojadinovic A, Anam K, et al.Int Wound J. 2009; 6:11-21 Click here to read...
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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease – A new navigated focal brain therapy

Ultrasound-based brain stimulation techniques offer an exciting potential to modulate the human brain in a...
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Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...
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Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

he physical shaking of the tissue by the shock waves leads to a mechanotransduction; the...
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The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...
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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

Prof. Hilde Beele (MD), Steven Smet, Francis Ramboer, at Ghent University Hospital faced up to the great...
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Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

d’Agostino MC., Sukubo NG., Tibalt W., Respizzi S., Locati M.,Int J Surg. 2015 Dec; 1-72015 Click...
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Benefits of Spark Wave Therapy in neuronal regeneration

(MTS Science) – Extracorporeal shock wave therapy (ESWT) is widely used in clinical practice. In addition to...
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Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

This study investigated the plasma protein expression in the extracorporeal shock wave therapy group and...
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Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Swarc et al. 20th ISMST Congress in San Sebastian, Spain Abstract P28 Click here to...
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Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Peyronie’s Disease (PD), and Sexual Rehabilitation After Radical Prostatectomy With Special Focus on Technical Aspects...
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Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Placebo controlled double-blinded, prospectively randomized clinical trial with 17 patients (11 verum, 5 placebo) for evaluation of cellulitetreatment with Acoustic Wave Therapy, (AWT(®))...
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Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...
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The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

The application of orthodontic force evokes an inflammatory reaction resulting in tooth movement. Shockwave therapy...
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Shockwave Therapy Of The Heart​

Ischemic heart disease represents a collective term for a continuous disease pathophysiology, ranging from acute...
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Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...
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Acoustic Field of a Ballistic Shock Wave Therapy Device

Abstract—Shock wave therapy (SWT) refers to the use of focused shock waves for treatment of...
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Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Carlotta Scarpa, MD, PhD, Vincenzo Vindigni, MD, PhD, and Franco Bassetto, MD Acoustic waves are mechanical waves...
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Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Stojadinovic A, Elster E, Anam EA, et al.Angiogenesis. 2008; 11(4):369-380 Click here to read more.
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Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

PubMed (Urology Department, Sheba Medical Center, Ramat-Gan, Israel; Ruth and Bruce Rappaport Faculty of Medicine,...
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Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

(Yousef Marwan, MBBS, Wael Husain, MBBS, FRCSC , Waleed Alhajii, MBBS, MSc, Facharztb , Magdy...
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Influence of medical shock waves on healthy muscle tissue

Competitive sport requires each athlete to be at peak performance at all times. This is...
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Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...
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Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

 (Georgia Urology, Atlanta, USA. 2018) Testosterone in males is produced in the testicles. With aging...
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The Roll of Spark Waves in the Management of Chronic Wounds.

Antibiotic-resistant bacterial colonies often produce biofilms (a defensive mechanism that creates a physical protective barrier...
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​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

The use of non-invasive brain therapies has become a hot topic recently. Alzheimer’s and Parkinson’s...
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Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

A review of preclinical studies – Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel treatment...
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Equine extracorporeal shock wave therapy

Extracorporeal shock wave therapy (ESWT) is an accepted form of treatment for chronic cases of...
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Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Antonic et al., 2018Wound medicine 20 (2018) 1-6https://doi.org/10.1016/j.wndm.2017.11.0012018 Click here to read more.
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Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

Predictive models permitting individualized prognostication for patients with fracture nonunion are lacking. The objective of...
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Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

This study aimed to investigate PDL’s cytokine concentration fluctuations after induction of orthodontic force with...
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Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal...
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COVID-19 pneumonia: different respiratory treatment for different phenotypes?

The Surviving Sepsis Campaign panel (ahead of print, DOI: 10.1007/s00134-020-06022-5) recently recommended that “mechanically ventilated...
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Set up Instructions

Video for setting up the device, inserting the applicator and water cartridge, and how to...
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Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor...
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Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Dental implants are a routine procedure within the therapeutic range of dentists. Many loading protocols...
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Unfocused extracorporeal shock waves induce anabolic effects in rat bone

van der Jagt OP, Piscaer TM, Schaden W, et al.J Bone Joint Surg Am. 2011; 93(2):38-48...
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Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

The objective of this study is to demonstrate the efficacy and safety of AWT(®), combining two different mechanical...
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Effect of shockwave therapy on orthodontic tooth movement

ESWT delays orthodontic tooth movement in rats and promotes osteoblast and osteoclast differentiation.​ Click here...
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Shock wave treatment of muscle stem cells – a new implementation for regeneration

Fuchs et al. 20th ISMST Congress in San Sebastian, Spain Abstract P29 Click here to...
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Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Extracorporeal shockwave therapy (ESWT) is used in a number of indications in the medical field....
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ESWT for Acute and Chronic Soft Tissue Wounds

Wolfgang Schaden, M.D., Richard Thiele, M.D., Christine Kölpl, M.D., Michael Pusch, M.D., Aviram Nissan, M.D.,...
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Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment: A Systematic Review of the Literature

Robert Dymarek, PhD, PT; Tomasz Halski, PhD, PT; Kuba Ptaszkowski, PhD, PT; Lucyna Slupska, PhD,...
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Successful treatment of nonunions with orthogold280

A pseudarthrosis is defined as a non healing fracture from which a false joint develops....
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FDA Devices and Indications

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Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...
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Treatment of stress urinary incontinence with low-intensity extracorporeal shock wave therapy in a vaginal balloon dilation induced rat model

To investigate the outcomes and mechanisms of low-intensity extracorporeal shock wave therapy (Li-ESWT) on stress...
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CLEARANCES

Lithotriptor, Extracorporeal Shock-Wave, Urological – LithoGoldMassager, Therapeutic, Electric – DermaGold; OrthoGold; UroGoldMassager, Therapeutic, Electric –...
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The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria;  AUVA Trauma Center Meidling, Vienna, Austria; ...
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Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Falkensammer et al.Clin Oral Investig. 2014 Dec;18(9):2187-92. doi: 10.1007/s00784-014-1199-0.  Click here to read more.
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Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...
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Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis,...
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Extracorporeal shock wave therapy for nonunion of the tibia

Delayed and nonunion of the tibia are not uncommon in orthopedic practice. Multiple methods of...
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Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...
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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

From Henry M. Jackson Foundation for Advancement in Military Medicine, Rockville, MD; Combat Wound Initiative...
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Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

Shockwave therapy (SWT) represents a promising regenerative treatment option for patients with ischemic cardiomyopathy. Although...
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Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

CREST syndrome is a variant of systemic sclerosis, which affects a relatively small number of...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

As new approaches for peripheral nerve regeneration are sought, there is an increasing demand for...
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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

(MTS Science) – Peripheral nerve injuries affect millions of people every year. After trauma or surgery, patients...
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The Applied Mechanical Vibration as Extracorporeal Shock Wave

Maria Cristina D’Agostino, Simona Maria Carmignano, and Andrea Saggini Click here to read more.
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Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Scaphoid nonunion remains challenging for hand surgeons. Several treatment options are available such as: non-vascularized or...
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Extracorporal SoftWave Treatment to Improve Nerve Regeneration

Extracorporeal softwave treatment is CE certified in Austria, Europe and licensed for indications like achillodynia,...
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Macrophage migration induces angiogenesis in ischemic myocardium after direct epicardial shock wave treatment

Holfeld et al. Thorac. Cardiovasc. Surg. (2012). doi:10.1055/s-0031-1297858 Click here to read more.
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First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

IRB study at Georgia Urology, Atlanta, USA – Since 2007 at least 250.000 ED patients have...
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Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

The authors of several studies have recommended extracorporeal shock-wave therapy as an alternative to surgical...
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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...
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​Exosomes and Cardiovascular Protection

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called...
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Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Schaden W, Thiele R, Kolpl C, et al.J Surg Res. 2007; 143:1-12 Click here to read...
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Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Hazan-Molina H., Reznick AZ., Kaufman H., Aizenbud D.Arch Oral Biol. 2013 Feb;58(2):142-50. Click here to read...
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The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

(Shih-Feng Lin, Yi-Jen Chen, Hung-Pin Tu , Chia-Ling Lee, Ching-Lin Hsieh , Wen-Lan Wu ,...
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The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...
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Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Tepeöylü et al.Journal of Tissue Engineering and Regenerative Medicine, 12(1), e486–e494. https://doi.org/10.1002/term.2317.2018 Click here to read...
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Penile low intensity shock wave therapy for PDE5i non responders: A prospective, randomized, placebo-controlled study

Fundació Puigvert, Barcelona, Spain European Congress of Andrology, Rotterdam, Netherlands Click here to read more.
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Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Nowadays, the search for the ideal body is related to internal dissatisfactions that generate low...
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Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Currently, there are no effective therapy strategies for idiopathic, non-organic vulvodynia in women. ESWT (extracorporeal...
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Extracorporeal shock wave therapy: clinical applications and regulation

Shock wave therapy is a relatively new modality for use in equine practice. The application...
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Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Many patients with Coronavirus disease 2019 (COVID-19) suffer from shortness of breath and severe chest...
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Shock wave therapy alone has no impact on cancer growth

Cancer remains one of the leading causes of morbidity and mortality throughout the world. Several...
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Shockwave Therapy Helping Patients With Peripheral Artery Disease

CBS News Stephanie Stahl reports. (Video) Click here to view video.
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UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Platelet-rich plasma (PRP) and extracorporeal shockwave therapy (ESWT) are both used for the treatment of...
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Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Schaden W, Mittermayr R.Jatros Orthopädie & Rheumatologie. 5/2011; 72-74 Click here to read more.
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Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...
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Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

Periodontal inflammation with alveolar bone resorption is a hallmark of periodontitis. We hypothesized that extracorporeal...
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Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Methods: Sixty SD rats were divided into five groups. Group I was the control and...
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Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Department of Urology, Eastern Virginia Medical School, Norfolk, VA, *Division of Urologic Surgery, University of...
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Athletic therapy (Mts-Science)

In modern society today, sport activity is becoming increasingly important. Reasons include more free time,...
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Efficacy of Unfocused Medium-Intensity Extracorporeal Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

Extracorporeal shock wave therapy (ESWT) is a promising treatment for plantar fasciitis (PF), however, treatment...
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Cleveland Clinic – Low Intensity Shockwaves In Urology

Cleveland Clinic Daniel Shoskes, MD – As urologists, we have decades of experience with extracorporeal shockwave lithotripsy for...
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End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

A novel coronavirus (2019-nCoV) was identified as the cause associated with emerging pneumonia (COVID-19) detected...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Breast cancer diagnosis and treatment with sentinel lymph node biopsy, axillary lymph node dissection and...
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OrthoGold 100TM

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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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ISSWSH Abstract

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Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

SoftWave® Tissue Regeneration Technologies, a disruptive bio-medical device company, announces the beginning of a trial...
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Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Zins et al.Angiogenesis, 13(4), 293–304. https://doi.org/10.1007/s10456-010-9186-9. Abstract Impaired wound healing is a persistent clinical problem which...
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Extracorporeal shock waves, a new non-surgical method to treat severe burns

Department of Plastic, Aesthetic and Reconstructive Surgery and Burn Center Vall d’Hebron University Hospital, Autonomous...
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Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Mittermayr R, Antonic V, Hartinger J et al .Wound Repair Regen. 2012 Jul;20(4):456-65 Click here to...
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Shock waves promote spinal cord repair via TLR3

Spinal cord injury (SCI) remains a devastating condition with poor prognosis and very limited treatment...
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​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

In this prospective design study the effects of low-energy partially focusedextracorporeal generated shock waves (ESW)...
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Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Dr. Slezak et al., Department of Physics Utah Valley University Orem, USA21th ISMST Congress in...
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Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Erectile dysfunction is highly prevalent in type II diabetes mellitus.Low intensity extracorporeal shock wave therapy...
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In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Journal of Sexual Medicine (Guiting Lin MD PhD, Amanda B. Reed-Maldonado MD, Bohan Wang MD,...
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Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost...
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LL37 and shock waves

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Stem cells pose risk, offer promise

Providing the therapy involves using an FDA cleared device with “genuine” shock waves, according to...
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In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Schuh et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into...
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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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Cellular mechanotransduction: putting all the pieces together again

Vascular Biology Program, Departments of Pathology and Surgery, Harvard Medical School and Children’s Hospital, Boston,...
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Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as...
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Alternative Treatment for Erectile Dysfunction with the Urogold 100™

MTS Science Published on Jun 21, 2016 – The improvement of Erectile Dysfunction through the treatment with...
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Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

PRESS RELEASE PR Newswire 2018 – Comprehensive Urology Medical Group, one of the nation’s leading...
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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Ultrasound based brain stimulation techniques may become a powerful new technique to modulate the human...
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Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

MTS-Science Low-intensity extracorporeal shock wave therapy (LI-ESWT) is of great clinical interest for the treatment...
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Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

We prospectively studied extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder in...
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Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...
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Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Anna M Larking, Sophie Duport Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, Michael Clinton...
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Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

For almost 30 years, extracorporeal shock wave therapy has been clinically implemented as an effective...
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Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Focused extracorporeal shockwave therapy (ESWT) has been demonstrated to improve wound healing and skin regeneration such as in burn...
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​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Rajendra Kashinath Shimpi, Ravi Jineshkumar Jain Department of Urology and Genito-Urinary Surgery, Ruby Hall Clinic,...
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Zapping chronic tendon pain

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Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Cyrill Slezak Beijing, May 24TH, 2019 Click here to read more.
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​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...
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ESWT for resident stress fractures in athletes.

Stress fractures are major concerns with athletes. It is sometimes difficult to repair, resulting in...
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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...
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Extracorporeal shockwave treatment for chronic diabetic foot ulcers

Seventy-two patients with 72 chronic diabetic foot ulcers were randomly divided into two groups of...
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Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

American Urological Association 2017 – American Urological Association. Dr. Tom Lue addressing erectile dysfunction during...
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MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science​  – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and...
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Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...
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Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

Postischemic cardiomyopathy remains one of the disorders in urgent need of effective noninvasive therapy. It...
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Heart Regeneration becomes Reality!

Regeneration of infarcted heart muscle remained a dream of modern medicine despite of comprehensive research...
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Biological mechanism of shockwave in bone

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through...
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Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Enhancement of flap survival through extracorporeal shock wave treatment (ESWT) is a promising new technique;...
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Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...
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The effect of shock waves on in vitro cartilage development in silk scaffolds

Szwarc et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...
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Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Holfeld J., Zimpfer D., Stojadinvic A., et al.J Tissue Eng Regen Med.  Click here to...
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Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and has presented...
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Current concepts of shockwave therapy in stress fractures

Stress fractures are common painful conditions in athletes, usually associated to biomechanical overloads. Low risk...
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Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated...
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​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...
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Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...
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Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Extracorporeal Shock Wave Research Unit, Department of Anatomy II, Ludwig-Maximilians-University of Munich, Pettenkoferstr.​ Extracorporeal shock wave...
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Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Tissue Regeneration Technologies – A four patient pilot trial was conducted in 2018 including four...
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ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Hercher et al.TERMIS World Congress 2018 in Kyoto, Japan Click here to read more.
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Ultrasound Brain Stimulation Piloted in Alzheimer Study

Patients with probable Alzheimer disease (AD) had sustained memory improvements months after ultrasound brain stimulation...
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Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Previously we have shown that epicardial shock-wave therapy improves left ventricular ejection fraction (LVEF) in...
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Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but...
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​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue...
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FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Professor Dr.-Ing. habil. Axel E. Theuer Click here to read more.
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Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Hausner t. et al.Experimental Neurology, 236(2), 363–370. https://doi.org/10.1016/j.expneurol.2012.04.019. Click here to read more.
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Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice,...
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MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Pain of the musculoskeletal system can seriously restrict the mobility of the affected persons and...
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Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Priglinger et al.Cytotherapy. 2017 Sep;19(9):1079-1095. doi: 10.1016/j.jcyt.2017.05.010. Epub 2017 July 19, 2017 Click here to read...
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Angiogenic response upon shock wave treatment of the ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Fully healed, Ordonez flourished for Tigers using ESWT

To fix an ailing knee that would not heal because blood had stopped circulating to...
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Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

(Dr Irwin Goldstein MD) Analogy to blood flow imparting physical forces – shear stress – onto...
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Biologic Response

LL37 and shock waves

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing by ATP release coupled extracellular signal-regulated kinase (ERK) activation

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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