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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

​Exosomes and Cardiovascular Protection

softwave device with water water blue background

What are the Side Effects of SoftWave Therapy

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Shock wave application to cell cultures

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Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Shockwave Therapy for Calcific Tendonitis

Non-Surgical Alternatives for Degenerative Disc Disease Treatment

Non-Surgical Treatment Options for Degenerative Disc Disease

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

The effect of shock waves on in vitro cartilage development in silk scaffolds

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

Alternative Treatment using Shockwave for Erectile Dysfunction

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

The link between shockwaves and innate immunity – the main working mechanism?

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Shockwave Therapy: Does it Hurt?

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Extracorporeal Shock Wave Therapy: Current Evidence

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Zapping chronic tendon pain

Indications for shockwaves in veterinary medicine

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Elucidating the molecular mechanisms underlying cardiac shock wave therapy

ISMST (International Society for Medical Shockwave Treatment)

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

Neuropathy

Shockwave Therapy for Neuropathy

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Test43212

Current concepts of shockwave therapy in stress fractures

Mesenchymal stem cells: Myths and reality

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

How Does Shockwave Therapy Work?

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Angiogenic response upon shock wave treatment of the ischaemic muscle

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

ESWT Therapy for Treatment of Keloid Scars

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Analysis of treatment protocols: application of ESWT for wound healing disorders

Shock wave treatment enhances stemness and preserves multipotency

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Shock Waves Reach Dental Implantology (Spanish)

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

4 U. S. Patents issued on July 19, 2022

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LL37 and shock waves

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Best Shockwave Therapy Machine For Providers

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The influence of comorbidities – ESWT for chronic soft tissue wounds

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

Shock waves induce angiogenesis via exosome release

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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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IVSWT Water Bath V2.0 Manual

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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CM Shockwave Before And After Use

​Antibacterial effects of extracorporeal shock waves

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Benefits of Spark Wave Therapy in neuronal regeneration

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Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines: Cost, Efficacy, & Alternatives

Best Treatment for Tennis Elbow Relief

Fully healed, Ordonez flourished for Tigers using ESWT

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

AUVA letter‒ Successful treatment of delayed and non-union fractures

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

Peripheral Nerve Regeneration

Shockwave Therapy for Achilles Tendonitis

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Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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MTS Spark WaveTM Technology and its mechanism of action in wound management

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

ESWT for Acute and Chronic Soft Tissue Wounds

Shock waves promote spinal cord repair via TLR32

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Veterinary wound care case study

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Shockwave therapy in stress fractures

Biological mechanism of shockwave in bone

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Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

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Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Principles of Shock Wave Therapy

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

10 Natural Ways to Find Pain Relief

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Erectile Dysfunction before and after results under ultrasound

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Macrophage migration induces angiogenesis

ESWT minimizes ischemic tissue necrosis…

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Scientific Reports – Gene transfection by shock waves

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

ISSWSH Abstract

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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Acoustic Field of a Ballistic Shock Wave Therapy Device

Effect of shockwave therapy on orthodontic tooth movement

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

Test12343

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Shock wave treatment for in vitro engineering applications

Spark Wave® Therapy Improves Full Thickness Skin Defects

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

ESWT for resident stress fractures in athletes.

SDSM Spine pain protocol

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

How to Manage Pain Without Drugs

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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The Physics of Shock Wave Lithotripsy

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Managing Pain with Shockwave Therapy for Muscles

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The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

ESWT for retracting scars of the hand

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

EPAT Therapy for Plantar Fasciitis vs Alternatives

Alternatives to Cortisone Shots

Ultrasound Brain Stimulation Piloted in Alzheimer Study

​Extracorporeal shock wave therapy: What? Why? Safety?

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Spark Wave® Therapy Ameliorates Urinary Incontinence

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Plantar Fasciitis Medical Devices That Relieve Pain

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Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Optimization of screw fixation in rat bone with extracorporeal shock waves

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Ultrasound Based Brain Stimulation

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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