PATIENTS    |   BECOME A PROVIDER    |   PROVIDER PORTAL    |   PROVIDER SEARCH    |   REIMBURSEMENT

SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

,

Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

,
Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

,

Equine extracorporeal shock wave therapy

Macrophage migration induces angiogenesis

Shock waves induce angiogenesis via exosome release

,

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

EPAT Therapy Costs for Patients & Practices

What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Shockwave Therapy Helping Patients With Peripheral Artery Disease

How Shockwave Therapy Breaks Down Scar Tissue

Focused vs Radial Shockwave Therapy Machines Explained 

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

,

Treatment of stress urinary incontinence

,

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

Extracorporeal shock wave therapy for nonunion of the tibia

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Shock wave application to cell cultures

,

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Erectile Dysfunction before and after results under ultrasound

Dr Irwin Goldstein Dinner Presentation – Nashville

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

,

Extracorporeal Shock Wave Therapy

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

DolorClast Therapy- Mechanism, Indications, and Clinical Evidence

DolorClast Therapy: What Is It & Does It Work for Patients?

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

,

Indications for shockwaves in veterinary medicine

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

,

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

,

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

,

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Cleveland Clinic – Low Intensity Shockwaves In Urology

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Shock wave treatment enhances stemness and preserves multipotency

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

,
Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

ESWT in skin & aesthetic indications

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

MTS Spark Wave Publications – Science Telegram

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Best Treatment for Tennis Elbow Relief

EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

Extracorporeal shockwave therapy for treatment of keloid scars

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

,
Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

EPAT Therapy for Plantar Fasciitis vs Alternatives

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

,

​The biologic effects of SoftWaves and rationale for spine and brain therapy

CM Shockwave Before And After Use

Shock wave therapy for systemic sclerosis

,

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

,

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

ESWT minimizes ischemic tissue necrosis…

ESWT Therapy for Treatment of Keloid Scars

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Stem cells pose risk, offer promise

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

Extracorporeal shock wave therapy: clinical applications and regulation

MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Benefits of Spark Wave Therapy in neuronal regeneration

,

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

,

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

,

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

Mechano-transduction effect of shock waves

,

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

Scientific Reports – Gene transfection by shock waves

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Storz Modulith Shockwave Systems- Mechanisms, Clinical Context, & Alternatives

Storz Modulith Shockwave Machines: Efficacy & Alternatives Explored

,
10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

,

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Acoustic Wave Therapy vs Shockwave Therapy

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Ultrasound Brain Stimulation Piloted in Alzheimer Study

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

The link between shockwaves and innate immunity – the main working mechanism?

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Evaluation of extracorporeal shock wave therapy for osteoarthritis

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Using Sound to Battle Opioid Crisis

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Lohse – Busch ISMST Presentation

Effects of ESWT on glycosaminoglycan expression during bone healing

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

, , , ,

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

,

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

,
Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

TRT SoftWaves® – a new regenerative therapy for paraplegia

,

4 U. S. Patents issued on July 19, 2022

,

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

,

Mesenchymal stem cells: Myths and reality

Medispec Shockwave Devices- Efficacy & Alternatives

Medispec Shockwave Devices: Efficacy & Alternatives

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

EPAT Therapy Side Effects & Contraindications

Low Intensity Shockwave Therapy vs High Intensity: Which Works Best?

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

,

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Influence of medical shock waves on healthy muscle tissue

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

,
Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

,
Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Heart Regeneration becomes Reality!

LL37 and shock waves

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

,

Shock wave treatment of muscle stem cells – a new implementation for regeneration

Shock wave therapy for osteoinduction

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Biological mechanism of shockwave in bone

,

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

,

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

,

Test43212

Extracorporeal Shockwave Therapy for Arthritis Treatment

SoftWave Therapy for Knees

SoftWave Therapy vs. Stem Wave & Acoustic Wave Devices for Knee Pain

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

, ,

MTS Spark WaveTM Technology and its mechanism of action in wound management

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

, ,

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Spark Wave® Therapy Improves Cardiac Function

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Become a ProviderFind a Provider

Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

Click here to read more.
Read More

LL37 and shock waves

Click here to read more.
Read More

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Click here to read more.
Read More

Biological Principles – Mechanotransduction

Click here to read more.
Read More

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Click here to read more.
Read More

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
Read More

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Latest Basic Research Abstracts

Click here to read more.
Read More

Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
Read More

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
Read More

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
Read More
Become a ProviderFind a Provider