SoftWave Research

Newest Research

Chris Holt Takes the Helm as New CEO of SoftWave Tissue Regeneration Technologies, Ushering in a New Era of Growth

Amazon Healthcare veteran Chris Holt brings experience and a bold vision to lead SoftWave TRT's...

Seven Trends in Healing for 2023

Smith, William The pace of innovation in regenerative medicine keeps getting faster. At clinics across...

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Pain is an unwelcome visitor in our lives, often leaving us desperate for relief. However,...

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag)

A prospective, randomized, double‐blinded, controlled pilot trial of 24 abdominoplasty patients revealed that preoperative application...

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

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Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and has presented...

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated...

Shock wave treatment of muscle stem cells – a new implementation for regeneration

Fuchs et al. 20th ISMST Congress in San Sebastian, Spain Abstract P29 Click here to...

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

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The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

(Tz-Yan Lin, Jing-Ting Chen, Yu-Yu Chen, Tien-Wen Chen , Chia-Ling Lee, Chia-Hsin Chen, Mao-Hsiung Huang)...

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Hercher et al.TERMIS World Congress 2018 in Kyoto, Japan Click here to read more.

AUVA letter‒ Successful treatment of delayed and non-union fractures

Click here to read more.

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a form of energy transfer that is of...

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

American Urological Association 2017 – American Urological Association. Dr. Tom Lue addressing erectile dysfunction during...

Is surgery the only option for bone-on-bone?

Patients are stuck and searching for non-surgical alternatives. SoftWave is a cost-effective alternative to joint...

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

(Alexandra Aicher, MD; Christopher Heeschen, MD; Ken-ichiro Sasaki, MD; Carmen Urbich, PhD; Andreas M. Zeiher,...

The Best Alternatives to Rotator Cuff Surgery

Rotator cuff injuries are all-too-frequent in the United States, affecting millions of people throughout the...

The link between shockwaves and innate immunity – the main working mechanism?

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MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process...

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

We prospectively studied extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder in...

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

MTS-Science Low-intensity extracorporeal shock wave therapy (LI-ESWT) is of great clinical interest for the treatment...

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

The objective of this study was to determine the safety and efficacy of noninvasive lipolysis of excess adiposities overlying the lateral...

Biological mechanism of shockwave in bone

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through...

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy.

Quadlbauer et al.Arch Orthop Trauma Surg. 2019 Feb;139(2):281-293.2019 Click here to read more.

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Saggini R., Saggini A., Spagnoli A.M.Ultrasound in Med. & Biol. Vol. 42, No. 1, pp....

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Saggini et al. Int J Pharma Sci Res 2016, 3: 119 Click here to read more.

Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue...

Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

MTS Science – Several animal and human studies have evaluated the role of low-intensity extracorporeal shockwave...

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

In a prospective clinical trial, ESWT was performed consecutively 4 times over two weeks in...

STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new...

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

The authors of several studies have recommended extracorporeal shock-wave therapy as an alternative to surgical...

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

The objective of the study was to compare the effects of shockwave therapy and laser...

Influence of medical shock waves on healthy muscle tissue

Competitive sport requires each athlete to be at peak performance at all times. This is...

Heart Regeneration becomes Reality!

Regeneration of infarcted heart muscle remained a dream of modern medicine despite of comprehensive research...

Fully healed, Ordonez flourished for Tigers using ESWT

To fix an ailing knee that would not heal because blood had stopped circulating to...

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

(Dr Irwin Goldstein MD) Analogy to blood flow imparting physical forces – shear stress – onto...

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Holfeld J., Zimpfer D., Stojadinvic A., et al.J Tissue Eng Regen Med. Click here to...

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

Low bone mineral density (BMD) leads to metaphyseal fractures, which are considered of delayed, qualitatively...

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Click here to read more.

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...

ESWT minimizes ischemic tissue necrosis…

Rainer Mittermayr, MD, Joachim Hartinger, Vlado Antonic, MS, Alexandra Meinl, PhD, Sabine Pfeifer, Alexander Stojadinovic,...

Best Treatments for Tennis Elbow Relief

The road to recovery is not always easy, but SoftWave wants to make it as...

ESWT for resident stress fractures in athletes.

Stress fractures are major concerns with athletes. It is sometimes difficult to repair, resulting in...

Acoustic Field of a Ballistic Shock Wave Therapy Device

Abstract—Shock wave therapy (SWT) refers to the use of focused shock waves for treatment of...

Set up Instructions

Video for setting up the device, inserting the applicator and water cartridge, and how to...

ISMST (International Society for Medical Shockwave Treatment)

Click here to read more.

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

Powerpoint abstract. Click here to read more.

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Urology Section, Department of Surgery, University of Catania, Catania, Department of Urology, University of Florence, Andrology...

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Enhancement of flap survival through extracorporeal shock wave treatment (ESWT) is a promising new technique;...

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Patients with systemic sclerosis (SSc) often display Raynaud’s phenomenon and digital skin ulcers. As these...

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Dr. Slezak et al., Department of Physics Utah Valley University Orem, USA21th ISMST Congress in...

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

MTS Medical – First comparative report for MTS/TRT UroGold, (unfocused shockwaves “SoftWaves” ) and Radial/Ballistic waves,...

Shock wave therapy for systemic sclerosis

We studied the effects of ESWT in 8 SSc female patients who received 4 consecutive...

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Holfeld et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...

Efficacy of extracorporeal shockwave therapy (ESWT) for male chronic pelvic pain syndrome: a phase III, randomized, double blind controlled with placebo study 

Ramon et al., Hospital Quiron Barcelona, Spain 20th ISMST Congress in San Sebastian, Spain.Poster Session...

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

(Wei Wei, Hua-yu Tang, Yu-zhi Li, Tian-shu Wang) – : Previous clinical trials have reported that...

Peripheral Nerve Regeneration

Most people are familiar with the central nervous system, i.e. the brain and spinal cord,...

Optimization of screw fixation in rat bone with extracorporeal shock waves

Koolen et al.Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23615. Click here to read more.

Indications for shockwaves in veterinary medicine

Click here to read more.

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Fleckenstein et al.Arch. Phys. Med. Rehabil. 98, 923–930 (2017). Click here to read more.

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Many patients with Coronavirus disease 2019 (COVID-19) suffer from shortness of breath and severe chest...

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Van der Jagt et al.Journal of Orthopaedic Research, 31(5), 768–775. https://doi.org/10.1002/jor.22258. Click here to read more.

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Stojadinovic A, Elster E, Anam EA, et al.Angiogenesis. 2008; 11(4):369-380 Click here to read more.

Extracorporeal shockwave therapy induces alveolar bone regeneration

Sathishkumar S, Meka A, Dawson D et al.J dent Res. 2008 Jul;87 Click here to read...

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

Mittermayer R, Hartinger J, Antonic V, et al.Ann Surg. 2011; 253(5):1024-32 Click here to read more.

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Director Kompass Health Associates, Centre for Regenerative Health, Sports Performance & Research – Auckland, New...

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Nägele et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant...

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...

Biological Principles – Mechanotransduction

Click here to read more.

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

IRB study at Georgia Urology, Atlanta, USA – Since 2007 at least 250.000 ED patients have...

4 U. S. Patents issued on July 19, 2022

SoftWave officially has been granted 4 new patents as of July 19, 200. They include...

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping and localized fat

Systematic review. – Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and...

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis,...

MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and...

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Thayná Melo de Lima Morais, Patrícia Froes Meyer, Liliane Santos de Vasconcellos, Julio Costa e Silva, Ito Ferreira e...

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

Shockwave therapy was originally developed to disintegrate urinary stones 4 decades ago1 . Since then,...

Mechano-transduction effect of shock waves in the treatment of lumbar facet joint pain:Comparative effectiveness evaluation

(Charles University in Prague, 2nd Faculty of Medicine, Department of Neurology, Prague, Czech Republic Center...

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

To evaluate the effect of extracorporeal shockwave therapy (ESWT) on pain and function in myofascial...

Prospective randomized phase II trial of accelerated reepithelialization

Christian Ottomann, MD, Alexander Stojadinovic, MD, FACS, Philip T. Lavin, PhD,§ Francis H. Gannon, MD,...

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Thomas A Davis, Alexander Stojadinovic, Khairul Anam, Mihret Amare, Shruti Naik, George E Peoples, Douglas...

Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

In this prospective design study the effects of low-energy partially focusedextracorporeal generated shock waves (ESW)...

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

(Department of Physical Therapy, Youngdong University) – [Purpose] The purpose of the present study was to...

The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria; AUVA Trauma Center Meidling, Vienna, Austria; ...

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

Extracorporeal softwave treatment is CE certified in Austria, Europe and licensed for indications like achillodynia,...

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The...

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Professor Dr.-Ing. habil. Axel E. Theuer Click here to read more.

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Schaden W, Thiele R, Kolpl C, et al.J Surg Res. 2007; 143:1-12 Click here to read...

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...

Shock wave treatment for in vitro engineering applications

Weihs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

Periodontal inflammation with alveolar bone resorption is a hallmark of periodontitis. We hypothesized that extracorporeal...

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

This RCT investigated the effect of non-invasive extracorporeal shockwaves on tooth mobility in orthodontic patients...

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

The objective of this study is to demonstrate the efficacy and safety of AWT(®), combining two different mechanical...

Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

Chronic muscle pain syndrome is one of the main causes of musculoskeletal pathologies requiring treatment....

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...

Exclusive Distribution Agreement With Cynosure – Aesthetics and Sexual Health Markets

Exclusive agreement to supply Cynosure LLC, a global leader in medical aesthetics, with its patented...

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Click here to read more.

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Click here to read more.

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

Shockwave therapy (SWT) represents a promising regenerative treatment option for patients with ischemic cardiomyopathy. Although...

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Falkensammer et al.Am J Orthod Dentofacial Orthop. 2014 Oct;146(4):413-22. doi: 10.1016/j.ajodo.2014.06.008. Click here to read...

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Department of Plastic, Aesthetic and Reconstructive Surgery and Burn Center Vall d’Hebron University Hospital, Autonomous...

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Priglinger et al.Cytotherapy. 2017 Sep;19(9):1079-1095. doi: 10.1016/j.jcyt.2017.05.010. Epub 2017 July 19, 2017 Click here to read...

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

Zins et al.Angiogenesis, 13(4), 293–304. https://doi.org/10.1007/s10456-010-9186-9. Abstract Impaired wound healing is a persistent clinical problem which...

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...

Extracorporeal shock wave therapy for nonunion of the tibia

Delayed and nonunion of the tibia are not uncommon in orthopedic practice. Multiple methods of...

Exosomes and Cardiovascular Protection

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called...

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Hexsel D, Camozzato FO, Silva AF, Siega Cellulite is a commonality among most women and some men. As...

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

National Institutes of Health (Xin Zhang, James D. Krier, Carolina Amador Carrascal, James F. Greenleaf, Behzad...

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Extracorporeal shock wave therapy (ESWT) uses acoustic pulses to treat certain musculoskeletal disorders. In this...

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous...

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Currently, there are no effective therapy strategies for idiopathic, non-organic vulvodynia in women. ESWT (extracorporeal...

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

For almost 30 years, extracorporeal shock wave therapy has been clinically implemented as an effective...

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as...

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...

ESWT in skin & aesthetic indications

ESWT in skin graft epithelialization 3 days faster healing. Click here to read more.

Mesenchymal stem cells: Myths and reality

Mesenchymal stem cells (MSCs; also called mesenchymal stromal cells) have received much attention during the...

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

(Non-invasive treatment of herniated discs by focused shockwave therapy) – In orthopedic practice meets a number...

Physical Rehabilitation Using Shockwave Therapy

Injuries can have a serious impact on lifestyle and health, which means that physical rehabilitation...

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but...

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Click here to read more.

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Bhojani et al.J. Urol. (2015). doi:10.1016/j.juro.2014.09.117. Click here to read more.

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

Wound healing disorders after vein harvesting for coronary artery bypass graft surgery increase morbidity and...

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Research Institute of Environmental Medicine at Heinrich-Heine University, D-40021 Duesseldorf,Germany In vivo measurements in 26...

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

d’Agostino MC., Sukubo NG., Tibalt W., Respizzi S., Locati M.,Int J Surg. 2015 Dec; 1-72015 Click...

Successful treatment of nonunions with orthogold280

A pseudarthrosis is defined as a non healing fracture from which a false joint develops....

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Preliminary results – (Caritas-Krankenhaus St. Josef, Klinik f ü r Plastische und Ä sthetische, Hand- und...

Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Click here to read more.

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Click here to read more.

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Maria Cristina D’Agostino, Simona Maria Carmignano, and Andrea Saggini Click here to read more.

Veterinary wound care case study

The following images are of dog bites wounds sustained by a foal approximately one week...

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Click here to read more.

MTS Spark Wave Publications – Science Telegram

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Unfocused extracorporeal shock waves induce anabolic effects in rat bone

van der Jagt OP, Piscaer TM, Schaden W, et al.J Bone Joint Surg Am. 2011; 93(2):38-48...

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

van der Jagt OP, Schaden W, van Schie H et al.Orthopaedic Research Society. 2008; Poster No....

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Lobenwein et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Alternatives to Surgery

Many people with injuries or chronic pain may feel as though surgery is their only...

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis

The goal for treating osteoarthritis (OA) is finding ways to decrease joint pain and dysfunction...

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...

Stem cells pose risk, offer promise

Providing the therapy involves using an FDA cleared device with “genuine” shock waves, according to...

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

An et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and...

Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...

Penile low-intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic erectile dysfunction since 2-10 years: A prospective, randomized, placebo-controlled study

Vinay et al., Fundació Puigvert, Barcelona, Spain 20th ISMST Congress in San Sebastian, Spain Click...

The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Extracorporeal shockwave therapy is a treatment modality, originally introduced into the clinic as lithotripsie, which...

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Graber et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Mittermayr R, Antonic V, Hartinger J et al .Wound Repair Regen. 2012 Jul;20(4):456-65 Click here to...

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

Pishchalnikov et al.Journal of Endourology / Endourological Society, 27(5), 631–9. https://doi.org/10.1089/end.2012.0611. Click here to read more.

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

A Systematic Scoping Review of Pre-Clinical Studies – Using Cochrane’s methodologic recommendations on scoping studies and...

How Does Shockwave Therapy Work?

If you are a healthcare provider, you likely prescribe a variety of treatments to help...

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt Department of General...

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

he physical shaking of the tissue by the shock waves leads to a mechanotransduction; the...

Effects of Low-Energy Shock Waves on Oral Bacteria

The objective of the present study was to determine any antibacterial effect of ESWT on...

Effectiveness of Extracorporeal Shock Wave Lithotripsy to treat Dystrophic Calcinosis Cutis

Delgado-Marquez et al.Actas Dermosifiliogr. 2015 Mar;106(2):140-3. doi: 10.1016/j.ad.2014.06.006. Click here to read more.

Extracorporeal shock wave therapy: clinical applications and regulation

Shock wave therapy is a relatively new modality for use in equine practice. The application...

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Anna M Larking, Sophie Duport Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, Michael Clinton...

Treatment for osteonecrosis of the femoral head: comparison of extracorporeal shock waves with core decompression and bone-grafting

Click here to read more.

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

2016 Dietz-Laursonn Click here to read more.

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Sansone V, D’Agostino MC, Bonora C, et al.Journal of Biological Regulators & Homeostatic Agents 2012; 26(1):29-37...

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...

Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Antonic et al., 2018Wound medicine 20 (2018) 1-6https://doi.org/10.1016/j.wndm.2017.11.0012018 Click here to read more.

ESWT for Acute and Chronic Soft Tissue Wounds

Wolfgang Schaden, M.D., Richard Thiele, M.D., Christine Kölpl, M.D., Michael Pusch, M.D., Aviram Nissan, M.D.,...

Extracorporeal Shock Wave Therapy: Current Evidence

The aim of this article is to provide a concise review of the basic science...

10 Natural Ways to Find Pain Relief

Chronic pain is a health issue in and of itself, one which affects around 50...

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Zimpfer D, Aharinejad S, Holfeld J, et al.J Thorac Cardiovasc Surg. 2009; 137(4):963-970 Click here to...

Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

As new approaches for peripheral nerve regeneration are sought, there is an increasing demand for...

Reduce Inflammation Naturally With Shockwave Therapy

Like all things, inflammation is good and healthy in moderation, but when it becomes chronic,...

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

(Yousef Marwan, MBBS, Wael Husain, MBBS, FRCSC , Waleed Alhajii, MBBS, MSc, Facharztb , Magdy...

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Davis T, Stojadinovic A, Anam K, et al.Int Wound J. 2009; 6:11-21 Click here to read...

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

(Georgia Urology, Atlanta, USA. 2018) Testosterone in males is produced in the testicles. With aging...

Shock wave therapy for osteoinduction

Koolen et al. 20th ISMST Congress in San Sebastian, Spain Abstract P33 Click here to...

SDSM Spine pain protocol

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

Extracorporeal shock wave therapy has been used in various clinical conditions as a result of...

How to Manage Pain Without Drugs

Pain is a natural part of life and serves a purpose by signaling to us...

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Ultrasound based brain stimulation techniques may become a powerful new technique to modulate the human...

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

This study aimed to investigate PDL’s cytokine concentration fluctuations after induction of orthodontic force with...

Effect of shockwave therapy on orthodontic tooth movement

ESWT delays orthodontic tooth movement in rats and promotes osteoblast and osteoclast differentiation. Click here...

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

ATLANTA, May 19, 2021 (Newswire) – SoftWave Tissue Regeneration Technologies patented extracorporeal shock wave device called...

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