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SoftWave Research

Newest Research

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SoftWave TRT Lands Prestigious VA Contract Revolutionizing Pain and Wound Management for Veterans

In a significant step forward for veterans' healthcare, SoftWave Tissue Regeneration Technologies (SoftWave TRT) has...
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Seven Trends in Healing for 2023

Smith, William The pace of innovation in regenerative medicine keeps getting faster. At clinics across...
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Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

This study investigated the plasma protein expression in the extracorporeal shock wave therapy group and...
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Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

The authors of several studies have recommended extracorporeal shock-wave therapy as an alternative to surgical...
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Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Schaden W, Thiele R, Kolpl C, et al.J Surg Res. 2007; 143:1-12 Click here to read...
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Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Many patients with Coronavirus disease 2019 (COVID-19) suffer from shortness of breath and severe chest...
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Extracorporeal shock wave therapy: clinical applications and regulation

Shock wave therapy is a relatively new modality for use in equine practice. The application...
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The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Extracorporeal shockwave therapy is a treatment modality, originally introduced into the clinic as lithotripsie, which...
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​Prospective randomized phase II trial of accelerated reepithelialization

Christian Ottomann, MD, Alexander Stojadinovic, MD, FACS,  Philip T. Lavin, PhD,§ Francis H. Gannon, MD,...
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Spark Wave® Therapy Improves Cardiac Function

Ischemic heart disease remains the leading cause of mortality (12.7%) worldwide, causing more than 7...
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Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Director Kompass Health Associates, Centre for Regenerative Health, Sports Performance & Research – Auckland, New...
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DUOLITH Shockwave Therapy: Benefits & Alternatives 

The advancement of medical technology, particularly in the realm of extracorporeal shockwave therapy, has offered...
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Evaluation of extracorporeal shock wave therapy for osteoarthritis

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and...
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Shock Waves Reach Dental Implantology (Spanish)

Lithotripsy or Shock Wave Therapy is proving to be an effective non-invasive treatment to regenerate...
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Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

MTS-Science Low-intensity extracorporeal shock wave therapy (LI-ESWT) is of great clinical interest for the treatment...
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Best Shockwave Therapy Machine For Providers

Extracorporeal shockwave therapy (ESWT) is a viable, growing treatment option for patients who are seeking...
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Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

Extracorporeal shock wave therapy has been used in various clinical conditions as a result of...
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Shockwave Therapy for Achilles Tendonitis

Achilles tendonitis is a common condition that causes pain and swelling in the Achilles tendon,...
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Effects of ESWT on glycosaminoglycan expression during bone healing

Several cases of delayed bone consolidation have been treated with extracorporeal shock wave therapy (ESWT) to improve bone...
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Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Elliot B. Lander, MD, Mark H. Berman, MD, Jackie R. See, MD – This pilot study...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Urological Times Cover – Scroll to Page 18 – 19

Urological Times – It’s hard to argue against an erectile dysfunction treatment that is potentially...
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Shock wave treatment of muscle stem cells – a new implementation for regeneration

Fuchs et al. 20th ISMST Congress in San Sebastian, Spain Abstract P29 Click here to...
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A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Alessandro Palmieri, Ciro Imbimbo, Nicola Longo, Ferdinando Fusco, Paolo Verze, Francesco Mangiapia, Massimiliano Creta ,...
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Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Liver cirrhosis is a life-threatening problem; a considerable proportion of patients with liver cirrhosis progress...
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The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock...
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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Since December, 2019, an outbreak of pneumonia caused by a novel coronavirus (SARS-CoV-2) has raised...
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Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

In a prospective clinical trial, ESWT was performed consecutively 4 times over two weeks in...
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Extracorporeal shockwave: mechanisms of action and physiological aspects…

Systematic review. – Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and...
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SoftWave Therapy for Knees

Knee pain is a widespread condition that affects a significant portion of the adult population...
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Stem cells pose risk, offer promise

Providing the therapy involves using an FDA cleared device with “genuine” shock waves, according to...
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Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and has presented...
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Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

(​Wei Wei, Hua-yu Tang, Yu-zhi Li, Tian-shu Wang) – : Previous clinical trials have reported that...
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Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Nägele et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...
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Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Breast cancer diagnosis and treatment with sentinel lymph node biopsy, axillary lymph node dissection and...
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Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Holfeld et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

The purpose of this meta-analysis was to assess the effects of extracorporeal shock wave therapy...
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ESWT minimizes ischemic tissue necrosis…

Rainer Mittermayr, MD, Joachim Hartinger, Vlado Antonic, MS, Alexandra Meinl, PhD, Sabine Pfeifer, Alexander Stojadinovic,...
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The Best Alternatives to Rotator Cuff Surgery

Rotator cuff injuries are all-too-frequent in the United States, affecting millions of people throughout the...
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EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

Extracorporeal Pulse Activation Technology (EPAT) has carved a significant niche in various medical fields, offering...
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Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Previously we have shown that epicardial shock-wave therapy improves left ventricular ejection fraction (LVEF) in...
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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

From Henry M. Jackson Foundation for Advancement in Military Medicine, Rockville, MD; Combat Wound Initiative...
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Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD, Bernd Hartmann, MD, Josh Tyler, MD, Heike Maier, MD, Richard Thiele, MD,Wolfgang...
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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Antonic et al., 2018Wound medicine 20 (2018) 1-6https://doi.org/10.1016/j.wndm.2017.11.0012018 Click here to read more.
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Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Angiotensin-converting enzyme (ACE2) has a multiplicity of physiological roles that revolve around its trivalent function:...
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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Ultrasound based brain stimulation techniques may become a powerful new technique to modulate the human...
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​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Karsten Knobloch • Beatrice Joest • Robert Kra ̈mer • Peter M. Vogt​ – Focused extracorporeal shockwave...
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Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Erectile dysfunction is highly prevalent in type II diabetes mellitus.Low intensity extracorporeal shock wave therapy...
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Extracorporeal Shockwave Therapy for Arthritis Treatment

Arthritis stands as a prevalent chronic joint condition, significantly impacting the quality of life for...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...
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Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

 (Georgia Urology, Atlanta, USA. 2018) Testosterone in males is produced in the testicles. With aging...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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​Extracorporeal shock wave therapy in periodontics: A new paradigm

The quest for exploring new frontiers in the field of medical science for efficient and...
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Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

SoftWave® Tissue Regeneration Technologies, a disruptive bio-medical device company, announces the beginning of a trial...
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SoftWave Shockwave Therapy for Pelvic Pain Relief

SoftWave Shockwave Therapy: A Revolutionary Approach to Pelvic Floor Therapy

In the dynamic world of healthcare, where every breakthrough counts, we present to you an...
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Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...
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Athletic therapy (Mts-Science)

In modern society today, sport activity is becoming increasingly important. Reasons include more free time,...
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Optimization of screw fixation in rat bone with extracorporeal shock waves

Koolen et al.Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23615. Click here to read more.
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Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Mayo Clinic – Extracorporeal shock wave therapy (ESWT) is a noninvasive treatment that involves delivery of shock...
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Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Pain is an unwelcome visitor in our lives, often leaving us desperate for relief. However,...
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The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Fuchs et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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SoftWave vs Shockwave Technology Explained 

In the dynamic world of medical advancements, SoftWave and Shockwave technologies stand out as pivotal...
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Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Swarc et al. 20th ISMST Congress in San Sebastian, Spain Abstract P28 Click here to...
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Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Tissue Regeneration Technologies – A four patient pilot trial was conducted in 2018 including four...
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Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Introduction: As of now, the role of extracorporeal shockwave therapy (ESWT) in the treatment of...
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MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science​  – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and...
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Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Department of Rehabilitation Medicine, Nan Lou of Chinese PLA General Hospital, Beijing, China – This study...
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SoftWave TRT Leads the Charge: Secures CPT Code Approval for Groundbreaking men’s sexual health and Shockwave Therapy

At the May meeting, the Current Procedural Terminology (CPT) Editorial Panel approved the reimbursement code...
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Extracorporeal shock waves, a new non-surgical method to treat severe burns

Department of Plastic, Aesthetic and Reconstructive Surgery and Burn Center Vall d’Hebron University Hospital, Autonomous...
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Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...
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Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

This study aimed to investigate PDL’s cytokine concentration fluctuations after induction of orthodontic force with...
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Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Focused extracorporeal shockwave therapy (ESWT) has been demonstrated to improve wound healing and skin regeneration such as in burn...
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ESWT for retracting scars of the hand

Department of Medical Sciences, Oral and Biotechnology, ‘‘G. D’Annunzio’’ University, Chieti, Italy;  Department of Dermatology,...
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Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Preliminary results – (Caritas-Krankenhaus St. Josef, Klinik f ü r Plastische und Ä sthetische, Hand- und...
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Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

Pishchalnikov et al.Journal of Endourology / Endourological Society, 27(5), 631–9. https://doi.org/10.1089/end.2012.0611. Click here to read more.
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Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Van der Jagt et al.Journal of Orthopaedic Research, 31(5), 768–775. https://doi.org/10.1002/jor.22258. Click here to read more.
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Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

MTS Science 2016. Urogenital indications such as painful penile angulation, erection problems and / or chronic...
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Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Mittermayr R, Antonic V, Hartinger J et al .Wound Repair Regen. 2012 Jul;20(4):456-65 Click here to...
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Effect of shockwave therapy on orthodontic tooth movement

ESWT delays orthodontic tooth movement in rats and promotes osteoblast and osteoclast differentiation.​ Click here...
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Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...
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Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

We tested whether shock wave (SW) offers additional benefits in improving left ventricular (LV) function...
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Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...
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Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Patients with systemic sclerosis (SSc) often display Raynaud’s phenomenon and digital skin ulcers. As these...
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Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

van der Jagt OP, Schaden W, van Schie H et al.Orthopaedic Research Society. 2008; Poster No....
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Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...
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Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Cell-based therapies with autologous adipose tissue–derived cells have shown great potential in several clinical studies...
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Effectiveness of Extracorporeal Shock Wave Lithotripsy to treat Dystrophic Calcinosis Cutis

Delgado-Marquez et al.Actas Dermosifiliogr. 2015 Mar;106(2):140-3. doi: 10.1016/j.ad.2014.06.006.  Click here to read more.
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Mesenchymal stem cells: Myths and reality

Mesenchymal stem cells (MSCs; also called mesenchymal stromal cells) have received much attention during the...
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Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Schaden W, Mittermayr R.Jatros Orthopädie & Rheumatologie. 5/2011; 72-74 Click here to read more.
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Prostatitis Treatment

Exploring Breakthroughs in Prostatitis Treatment: SoftWave Urogold Leading the Way

In the field of prostatitis treatment, patients yearn for relief from the burdensome symptoms of...
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Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Extracorporeal Shock Wave Research Unit, Department of Anatomy II, Ludwig-Maximilians-University of Munich, Pettenkoferstr.​ Extracorporeal shock wave...
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Plantar Fasciitis Medical Devices That Relieve Pain

Plantar fasciitis, a prevalent foot condition, often manifests as persistent heel pain, particularly acute in...
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The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Low-energy extracorporeal shock wave treatment (ESWT) is a relatively new therapeutic tool that is widely...
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Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...
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Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost...
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Shockwave Therapy for Plantar Fasciitis

Heel pain is deeply uncomfortable, and it can be tricky to treat. One common cause...
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Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

PRESS RELEASE PR Newswire 2018 – Comprehensive Urology Medical Group, one of the nation’s leading...
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The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...
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Extracorporeal Shock Wave Therapy: Current Evidence

The aim of this article is to provide a concise review of the basic science...
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How Li-ESWT Works for Patients w/ ED & Other Indications

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is becoming increasingly recognized in the medical community for...
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Can cellulite be treated with low-energy extracorporeal shock wave therapy?

The present study investigates the effects of low-energy defocused extracorporeal generated shock waves on collagen...
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Unfocused extracorporeal shock waves induce anabolic effects in rat bone

van der Jagt OP, Piscaer TM, Schaden W, et al.J Bone Joint Surg Am. 2011; 93(2):38-48...
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Technology Assessment “Wound Care” dermagold100

MTS-Science – ​Acute wounds are caused exogenously by traumatic (e.g. mechanical, chemical, thermical) or iatrogenic (e.g. surgical)...
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Treatment of scaphoid waist nonunion

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or...
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Shockwave Therapy Of The Heart​

Ischemic heart disease represents a collective term for a continuous disease pathophysiology, ranging from acute...
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Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

(Notarnicola, Maccagnano, Gallone, Mastromauro, Rifino, Pesce, Covelli , Moretti B) The physiotherapy treatment of low...
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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

(MTS Science) – Peripheral nerve injuries affect millions of people every year. After trauma or surgery, patients...
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The Applied Mechanical Vibration as Extracorporeal Shock Wave

Maria Cristina D’Agostino, Simona Maria Carmignano, and Andrea Saggini Click here to read more.
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Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...
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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...
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Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Falkensammer et al.Clin Oral Investig. 2014 Dec;18(9):2187-92. doi: 10.1007/s00784-014-1199-0.  Click here to read more.
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Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

Predictive models permitting individualized prognostication for patients with fracture nonunion are lacking. The objective of...
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Best Treatment for Tennis Elbow Relief

What is Tennis Elbow and What Causes It? Even if you’re not an avid tennis...
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Shockwave Therapy for Calcific Tendonitis

Shoulder pain is a prevalent complaint that affects millions of individuals worldwide. In fact, it’s...
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Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

(Department of Physical Therapy, Youngdong University) – [Purpose] The purpose of the present study was to...
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Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a form of energy transfer that is of...
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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Pain of the musculoskeletal system can seriously restrict the mobility of the affected persons and...
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Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Knowing the most effective treatment options for your patients is crucial for their speedy recovery....
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Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Research Institute of Environmental Medicine at Heinrich-Heine University, D-40021 Duesseldorf,Germany In vivo measurements in 26...
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Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...
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Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...
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The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Rani S, Ritter T – Wound healing is a complex process and often delayed in patients with...
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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

(​H. Lohse-Busch, U. Reime and R. Falland Outpatient Department for Manual Medicine – Movement Disorder...
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Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as...
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Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Dr. Slezak et al., Department of Physics Utah Valley University Orem, USA21th ISMST Congress in...
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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...
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Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

(Yousef Marwan, • Bashar Dahrab • Ali Esmaeel • Samir Abdulrazik Ibrahim • Jassim Al-Failakawi)...
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Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD,∗ Alexander Stojadinovic, MD, FACS, Philip T. Lavin, PhD, Francis H. Gannon, MD,...
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The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

(Shih-Feng Lin, Yi-Jen Chen, Hung-Pin Tu , Chia-Ling Lee, Ching-Lin Hsieh , Wen-Lan Wu ,...
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Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

The low-energy extracorporal shockwave is a scientifically approved method to activate respectively increase bone-turnover processes...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Extracorporeal Shock Wave Therapy for Hypertrophic Scars

Hypertrophic scars cause aesthetic concerns and negatively affect the quality of life. A gold standard...
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Shock Wave Therapy for ED: Does It Work?

For men, erectile dysfunction (ED) can be a challenge, causing feelings of frustration, anxiety, and...
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Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but...
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Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Sansone V, D’Agostino MC, Bonora C, et al.Journal of Biological Regulators & Homeostatic Agents 2012; 26(1):29-37...
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Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Extracorporeal shock wave therapy (ESWT) uses acoustic pulses to treat certain musculoskeletal disorders. In this...
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The effect of shock waves on in vitro cartilage development in silk scaffolds

Szwarc et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...
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The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria;  AUVA Trauma Center Meidling, Vienna, Austria; ...
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Physical Rehabilitation Using Shockwave Therapy

Injuries can have a serious impact on lifestyle and health, which means that physical rehabilitation...
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Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into...
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Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Yard DH.Renal & Urology News. 2011 Click here to read more.
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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Ultrasound-based brain stimulation techniques offer an exciting potential to modulate the human brain in a...
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Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

A review of preclinical studies – Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel treatment...
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A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

The objective of this study was to determine the safety and efficacy of noninvasive lipolysis of excess adiposities overlying the lateral...
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Extracorporeal shockwave therapy induces alveolar bone regeneration

Sathishkumar S, Meka A, Dawson D et al.J dent Res. 2008 Jul;87 Click here to read...
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Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Shogo Inoue, Tetsutaro Hayashi, Jun Teishima, Akio Matsubara Click here to read full article on...
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FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Professor Dr.-Ing. habil. Axel E. Theuer Click here to read more.
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Extracorporeal Shockwave Therapy for Kidney Stone Treatment

Kidney stones, a common urological condition causing significant morbidity worldwide, have historically challenged medical professionals...
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​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Treatment can be used alone or in combination with other therapies. Both young, athletic dogs...
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Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

A systematic review and meta-analysis of preclinical studies – Limited regeneration after nerve injury often leads...
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Shock wave therapy alone has no impact on cancer growth

Cancer remains one of the leading causes of morbidity and mortality throughout the world. Several...
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Zapping chronic tendon pain

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Biologic Response

LL37 and shock waves

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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