PATIENTS    |   BECOME A PROVIDER    |   PROVIDER PORTAL    |   PROVIDER SEARCH    |   REIMBURSEMENT

SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

,
What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Shock waves promote spinal cord repair via TLR32

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Shockwave Therapy Of The Heart​

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Using Sound to Battle Opioid Crisis

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

ESWT for resident stress fractures in athletes.

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Influence of medical shock waves on healthy muscle tissue

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Shockwave Machine for Providers

,

ESWT for retracting scars of the hand

Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

How Li-ESWT Works for Patients With ED & Other Indications

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

,

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

,

Spark Wave® Therapy Improves Full Thickness Skin Defects

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

,

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

,
Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

Extracorporeal shockwave therapy induces alveolar bone regeneration

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Effects of ESWT on glycosaminoglycan expression during bone healing

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

,
7 Red Flags That Signal a Risky Shockwave Device

Shockwave Therapy for Physical Therapists

Urological Times Cover – Scroll to Page 18 – 19

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

MTS Spark Wave Publications – Science Telegram

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Treatment of stress urinary incontinence

,

Biological mechanism of shockwave in bone

,

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

Mesenchymal stem cells: Myths and reality

​Antibacterial effects of extracorporeal shock waves

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

,

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

,

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

​Exosomes and Cardiovascular Protection

Novel Approach to Obtain an Activated Fat Graph

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

Angiogenic response upon shock wave treatment of the ischaemic muscle

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

,

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

,

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Cellular mechanotransduction: putting all the pieces together again

Is surgery the only option for bone-on-bone?

,
Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Athletic therapy (Mts-Science)

Reduce Inflammation Naturally With Shockwave Therapy

Shock wave therapy alone has no impact on cancer growth

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

,

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

,
Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

EPAT Therapy Side Effects & Contraindications

TRT SoftWaves® – a new regenerative therapy for paraplegia

,

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

The link between shockwaves and innate immunity – the main working mechanism?

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Sound Frequency Healing: The Spark of Life

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

EPAT Therapy for Plantar Fasciitis vs Alternatives

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

,
The Best Alternatives to Rotator Cuff Surgery

Alternatives to Rotator Cuff Surgery

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Effect of shock waves on macrophages

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Physical Rehabilitation Using Shockwave Therapy

,
OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

CM Shockwave Before And After Use

What are the Side Effects of SoftWave Therapy

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

What Is StemWave Therapy? How It Works, What It Costs & How It Compares

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Ultrasound Based Brain Stimulation

Shockwave Therapy for the Treatment of Cancer

Radial vs. Focused Shockwave Therapy: Clinical Deep Dive

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

, , , ,

SoftWave TRT vs Storz Shockwave Machines Compared

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

Shockwave therapy in stress fractures

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

, ,

Macrophage migration induces angiogenesis

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

,

Acoustic Field of a Ballistic Shock Wave Therapy Device

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

Shock Waves Reach Dental Implantology (Spanish)

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

MTS Spark WaveTM Technology and its mechanism of action in wound management

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

, ,

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Shock wave treatment for in vitro engineering applications

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Shock wave treatment enhances stemness and preserves multipotency

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Acoustic Wave Therapy vs Shockwave Therapy

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

,

Natural Remedies for Tendonitis

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Principles of Shock Wave Therapy

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

,

What Is Piezowave and How Does It Work?

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Can You Use a Shockwave Therapy Machine at Home?

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

,

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

,

ESWT Therapy for Treatment of Keloid Scars

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Dr Irwin Goldstein Dinner Presentation – Nashville

Dr. Lohse Bush, first brain treatments

EPAT Therapy Costs for Patients & Practices

Scientific Reports – Gene transfection by shock waves

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

,

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Become a ProviderFind a Provider

Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

Click here to read more.
Read More

LL37 and shock waves

Click here to read more.
Read More

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Click here to read more.
Read More

Biological Principles – Mechanotransduction

Click here to read more.
Read More

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Click here to read more.
Read More

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
Read More

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Latest Basic Research Abstracts

Click here to read more.
Read More

Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
Read More

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
Read More

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
Read More
Become a ProviderFind a Provider
SoftWave

CORPORATE OFFICE: 10000 Avalon Blvd, Suite 720, Alpharetta, GA  30009

PRODUCT SHIPMENTS: NOTE NEW SERVICE DEPT LOCATION: 3005 Chastain Meadows Pkwy, Suite 300, Marietta, GA 30066

[email protected]

(888) 862-6162

Technical Support (470) 494-6773

PATENT LIST

VA SSF Contract/Schedule Holder 

 

SoftWave C.O.E.

UPCOMING EVENTS

© Copyright 2026 SoftWave Tissue Regeneration Technologies | All Rights Reserved
Privacy Policy