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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Shockwave Therapy: Does it Hurt?

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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

The Roll of Spark Waves in the Management of Chronic Wounds.

Biological mechanism of musculoskeletal shockwaves

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Shock wave treatment of muscle stem cells – a new implementation for regeneration

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

ESWT for retracting scars of the hand

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Shock waves promote spinal cord repair via TLR32

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

Stem cells pose risk, offer promise

Erectile Dysfunction before and after results under ultrasound

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Shock wave therapy alone has no impact on cancer growth

Principles of Shock Wave Therapy

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Effect of shockwave therapy on orthodontic tooth movement

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

​Prospective randomized phase II trial of accelerated reepithelialization

Equine extracorporeal shock wave therapy

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

ISSWSH Abstract

The Best Alternatives to Rotator Cuff Surgery

The Best Alternatives to Rotator Cuff Surgery

Scientific Reports – Gene transfection by shock waves

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines: Cost, Efficacy, & Alternatives

Peripheral Nerve Regeneration

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

AUVA letter‒ Successful treatment of delayed and non-union fractures

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Shockwave Therapy for Plantar Fasciitis

Novel Approach to Obtain an Activated Fat Graph

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Using acoustic therapy to prevent opioid addiction.

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Is surgery the only option for bone-on-bone?

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Biological mechanism of shockwave in bone

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MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Motor and Sensory Schwann Cell Phenotype

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Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

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​Exosomes and Cardiovascular Protection

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Extracorporeal Shockwave Therapy for Arthritis Treatment

Benefits of Spark Wave Therapy in neuronal regeneration

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The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal Magnetic Transduction Therapy Explained

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

The link between shockwaves and innate immunity – the main working mechanism?

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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Mesenchymal stem cells: Myths and reality

Using Sound to Battle Opioid Crisis

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Natural Remedies for Tendonitis

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

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Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

Extracorporeal Shock Wave Therapy

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Indications for shockwaves in veterinary medicine

International Society for Medical Shockwave Treatment- ESWT BASIC PHYSICAL PRINCIPLES

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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MTS Spark WaveTM Technology and its mechanism of action in wound management

Alternative Treatments for Hip Replacement Surgery

Alternative Treatments for Hip Replacement Surgery

Extracorporeal shock wave therapy: clinical applications and regulation

Shockwave Therapy for Achilles Tendonitis

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The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Molecular changes in diabetics foot ulcers

Spark Wave® Therapy Improves Cardiac Function

Macrophage migration induces angiogenesis

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Sound Frequency Healing: The Spark of Life

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Alternative Treatment using Shockwave for Erectile Dysfunction

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

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Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Shock waves induce angiogenesis via exosome release

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Latest Basic Research Abstracts

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

ESWT minimizes ischemic tissue necrosis…

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

EPAT Therapy Side Effects & Contraindications

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Urological Times Cover – Scroll to Page 18 – 19

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Extracorporal SoftWave Treatment to Improve Nerve Regeneration

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Spark Wave® Therapy Ameliorates Urinary Incontinence

The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Natural Remedies for Tendonitis

Natural Remedies for Tendonitis

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

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Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Physical Rehabilitation Using Shockwave Therapy

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In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Doubts over heart stem-cell therapy

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ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Shockwave treatment enhances cell proliferation and improves wound healing

Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

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Treatment of stress urinary incontinence

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Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

SoftWave : Transforming Foot Pain Management with Advanced Shockwave Therapy

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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LL37 and shock waves

Acoustic Field of a Ballistic Shock Wave Therapy Device

low intensity softwave in use on arm on a table

What is Li-ESWT & How Does It Work?

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

MTS Spark Wave Publications – Science Telegram

Biological Principles – Mechanotransduction

Alteration Of Inflammatory Response By Shock Wave Therapy Leads To Reduced Calcification Of Decellularized Aortic Xenografts In Mice.

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

How Does Shockwave Therapy Work?

Shock wave treatment for in vitro engineering applications

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Extracorporeal shockwave therapy induces alveolar bone regeneration

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

The effect of shock waves on in vitro cartilage development in silk scaffolds

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

EPAT Therapy Costs for Patients & Practices

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Influence of medical shock waves on healthy muscle tissue

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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