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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Sticky Post

Seven Trends in Healing for 2023

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Alternatives to Surgery

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Effect of shock waves on macrophages

Latest Basic Research Abstracts

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

The Physics of Shock Wave Lithotripsy

Low-Intensity Shockwave Therapy May Be Beneficial for Women With Provoked Vestibulodynia

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Doubts over heart stem-cell therapy

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Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines: Cost, Efficacy, & Alternatives

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Angiogenic response upon shock wave treatment of the ischaemic muscle

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Extracorporeal Shockwave Therapy for Kidney Stone Treatment

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Extracorporeal shockwave: mechanisms of action and physiological aspects…

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Scientific Reports – Gene transfection by shock waves

How Shockwave Therapy Breaks Down Scar Tissue

EPAT Shockwave Therapy Efficacy & Alternatives Explained

EPAT Shockwave Therapy Efficacy & Alternatives Explained

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Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

Shockwave therapy in stress fractures

​Antibacterial effects of extracorporeal shock waves

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Benefits of Unfocused Li-ESWT for Erectile Dysfunction and Nocturia

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Treatment of stress urinary incontinence

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Revolutionary Approach to Pelvic Floor Therapy

SoftWave Shockwave Therapy: A Breakthrough for Pelvic Pain Relief

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Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

ESWT Therapy for Treatment of Keloid Scars

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Using acoustic therapy to prevent opioid addiction.

ESWT for retracting scars of the hand

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Motor and Sensory Schwann Cell Phenotype

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Minimally invasive treatment of Peyronie’s disease: evidence-based progress

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

Shockwave treatment enhances cell proliferation and improves wound healing

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

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Is surgery the only option for bone-on-bone?

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Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

ESWT for Acute and Chronic Soft Tissue Wounds

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Shockwave Therapy for Plantar Fasciitis

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Shock waves induce angiogenesis via exosome release

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Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Variable Sound -Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

​Prospective randomized phase II trial of accelerated reepithelialization

Set up Instructions

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Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Acoustic Field of a Ballistic Shock Wave Therapy Device

Empowering Recovery: SoftWave Urogold’s Breakthrough in Vaginismus Treatment

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The link between shockwaves and innate immunity – the main working mechanism?

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

SoftWave device

Does Piezowave Therapy Work for Patients?

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

DUOLITH Shockwave Therapy: Benefits & Alternatives 

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

LL37 and shock waves

Spark Wave® Therapy Improves Full Thickness Skin Defects

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Shock wave treatment for in vitro engineering applications

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Extracorporeal shockwave therapy induces alveolar bone regeneration

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

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Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

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Plantar Fasciitis Medical Devices That Relieve Pain

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Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Cleveland Clinic – Low Intensity Shockwaves In Urology

Shock wave therapy for systemic sclerosis

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Shock wave therapy alone has no impact on cancer growth

TRT SoftWaves® – a new regenerative therapy for paraplegia

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SoftWave TRT Leads the Charge: Secures CPT Code Approval for Groundbreaking men’s sexual health and Shockwave Therapy

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Extracorporeal shockwave therapy for treatment of keloid scars

Mechano-transduction effect of shock waves

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MTS Science White Paper – Softwave – Pain Therapy

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal Shock Wave Therapy

How Does Shockwave Therapy Work?

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Extracorporeal Shock Wave Therapy: Current Evidence

Shock Wave Therapy for ED: Does It Work?

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Using Sound to Battle Opioid Crisis

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Penile low-intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic erectile dysfunction since 2-10 years: A prospective, randomized, placebo-controlled study

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Effects of ESWT on glycosaminoglycan expression during bone healing

Extracorporeal shock wave therapy for nonunion of the tibia

SoftWave Shockwave Therapy for Pelvic Pain Relief

SoftWave Shockwave Therapy: A Revolutionary Approach to Pelvic Floor Therapy

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Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Extracorporeal Shockwave Therapy for Arthritis Treatment

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

SoftWave Tissue Regeneration Technologies Receives Innovative Technology Contract from Vizient For DermaGold®

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Shockwave Therapy for Achilles Tendonitis

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Effects of Low-Energy Shock Waves on Oral Bacteria

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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Spark Wave® Therapy Improves Cardiac Function

Current concepts of shockwave therapy in stress fractures

Mesenchymal stem cells: Myths and reality

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

SoftWave vs Shockwave Technology Explained 

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SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

The Concept of Spark Wave Therapy (Swt) Assisted Penile Augmentation

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

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Alternatives to Cortisone Shots

Benefits of Spark Wave Therapy in neuronal regeneration

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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Peripheral Nerve Regeneration

Foot application

EPAT Therapy Machines vs Competitors in Cost & Efficacy

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Fully healed, Ordonez flourished for Tigers using ESWT

Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Macrophage migration induces angiogenesis

Biological mechanism of shockwave in bone

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OrthoGold 100TM

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

The effect of shock waves on in vitro cartilage development in silk scaffolds

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Li-ESWT Devices Compared [Guide] 

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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