Ultrasound based brain stimulation techniques may become a powerful new technique to modulate the human brain in a focal and targeted manner. However, for clinical brain stimulation no certified systems exist and the current techniques have to be further developed. Here, a clinical sonication technique is introduced, based on single ultrashort ultrasound pulses (transcranial pulse...Read More

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but its mechanisms are not well understood. Previously, we found that Li-ESWT increased the expression of brain-derived neurotrophic factor (BDNF). Here we assessed the underlying signaling pathways in Schwann cells in vitro and in penis tissue in vivo after nerve injury....Read More

The purpose of this meta-analysis was to assess the effects of extracorporeal shock wave therapy (ESWT) on reducing spasticity immediately and 4 weeks after application of ESWT. [Subjects and Methods] We searched PubMed, TCL, Embase, and Scopus from their inception dates through June 2013. The key words “muscle hypertonia OR spasticity” were used for spasticity,...Read More

Ultrasound-based brain stimulation techniques offer an exciting potential to modulate the human brain in a highly focal and precisely targeted manner. However, for clinical applications the current techniques have to be further developed. We introduce a new ultrasound stimulation technique, based on single ultrashort ultrasound pulses (transcranial pulse stimulation, TPS) and describe a first navigable...Read More

Patients with probable Alzheimer disease (AD) had sustained memory improvements months after ultrasound brain stimulation in a small pilot study, found here. The noninvasive technique, called transcranial pulse stimulation (TPS), is designed to apply ultrashort ultrasound pulses to small brain areas. Click here to read more.Read More

The use of non-invasive brain therapies has become a hot topic recently. Alzheimer’s and Parkinson’s are major medical challenges in the context of our ageing society. The available treatments are limited, and such patients are therefore very important candidates to benefit from the clinical utility of new additional therapies. Click here to read more.Read More

Ultrasound based brain stimulation techniques bay become a powerful new technique to modulate the human brain in a focal and targeted manner. However, for clinical brain stimulation no certified systems exist and the current techniques have to be further developed. Here, a clinical sonication technique is introduced, based on a single ultrashort ultrasound pulses (transcranial pulse stimuation, TPS) which markedly...Read More

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases of energy. The best-known natural phenomenon is thunder following lightning. Another example is the “bang” an aircraft produces when it breaks the sound barrier. Both focused shock waves and unfocused sound waves are produced in these examples. Additionally, almost all...Read More

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new therapy system for the treatment of neurological diseases. The technology behind the NEUROLITH® is called Transcranial Pulse Stimulation (TPS). TPS consists of short acoustic pulses with an ultrasound frequency range that permits a well-focused stimulation of the brain at a depth of...Read More