Stem Cells Research

Stem Cells

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shock-wave (ESW) treatment has been shown to be effective in promoting the healing of...

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

The stromal vascular fraction (SVF) is a heterogeneous cell population derived from the adipose tissue....

Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue...

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

We tested whether shock wave (SW) offers additional benefits in improving left ventricular (LV) function...

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...

Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Human bone marrow stromal cells (hBMSCs) bear tremendous clinical potential due to their immunomodulatory properties...

Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated...

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Platelet-rich plasma (PRP) and extracorporeal shockwave therapy (ESWT) are both used for the treatment of...

Novel Approach to Obtain an Activated Fat Graph

One of the mainstays of facial rejuvenation strategies is volume restoration, which can be achieved...

Shock waves induce angiogenesis via exosome release

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Scientific Reports – Gene transfection by shock waves

Extracorporeal shock wave (SW) therapy has been studied in the transfection of naked nucleic acids...

Angiogenic response upon shock wave treatment of the ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...

Mesenchymal stem cells: Myths and reality

Mesenchymal stem cells (MSCs; also called mesenchymal stromal cells) have received much attention during the...

Cellular mechanotransduction: putting all the pieces together again

Vascular Biology Program, Departments of Pathology and Surgery, Harvard Medical School and Children’s Hospital, Boston,...

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Xi Ouyang , Xiaoyan Han , Zehong Chen, Jiafeng Fang, Xuna Huang and Hongbo Wei...

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Jieyuan Zhang, Junjie Guan, Xin Niu, Guowen Hu, Shangchun Guo , Qing Li , Zongping...

Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Cell-based therapies with autologous adipose tissue–derived cells have shown great potential in several clinical studies...

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

Mechanical stimulation of acute ischemic myocardium by shock wave therapy (SWT) is known to improve...

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

Postischemic cardiomyopathy remains one of the disorders in urgent need of effective noninvasive therapy. It...

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous...

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