Elliot B. Lander, MD, Mark H. Berman, MD, Jackie R. See, MD – This pilot study was used to evaluate safety and subjective out-comes in a small series of Peyronie’s disease patients using a combination of autologous stromal vascular fraction (SVF) and penile shock wave treat-ments. SVF can be procured and deployed into Peyronie’s plaques, en-abling the surgeons to procure and mobilize significant numbers of both adult mesenchymal stem cells and antiinflammatory cytokines released from the adipose collagen matrix after collagen digestion.