Jieyuan Zhang, Junjie Guan, Xin Niu, Guowen Hu, Shangchun Guo , Qing Li , Zongping Xie , Changqing Zhang and Yang Wang – Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) have emerged as a promising alternative for stem cell transplantation therapy. Exosomes derived from mesenchymal stem cells (MSC-Exos) can play important roles in repairing injured...Read More
The cells are then injected back into the patient, to help repair damaged tissue. Original claims that they differentiated into replacement cells have been rejected , and many clinicians now believe that the cells act by releasing molecules that cause inflammation, with an attendant growth of oxygen-delivering small blood vessels, in the damaged tissue. Click...Read More
Cell-based therapies with autologous adipose tissue–derived cells have shown great potential in several clinical studies in the last decades.The majority of these studies have been using the stromal vascular fraction (SVF), a heterogeneous mixture of fibroblasts, lymphocytes, monocytes/macrophages, endothelial cells, endothelial progenitor cells, pericytes and adipose-derived stromal/stem cells (ASC) among others. Although possible clinical applications...Read More
Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate lymphangiogenesis in vivo. The aim of this study was to investigate in vitro shockwave treatment (IVSWT) effects on lymphatic endothelial cell (LEC) behavior and lymphangiogenesis. We analyzed migration,proliferation, vascular tube forming capability and marker expression changes of LECs after IVSWT...Read More
Angiotensin-converting enzyme (ACE2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system (RAS), facilitator of amino acid transport, and the SARS-CoV and SARS-CoV-2 receptor. ACE2 is widely expressed, including, in the lungs, cardiovascular system, gut, kidneys, central nervous system, and adipose tissue. ACE2 has recently...Read More
A novel coronavirus (2019-nCoV) was identified as the cause associated with emerging pneumonia (COVID-19) detected in Wuhan on Jan 7th. Since the number of patients rising rapidly worldwide, COVID-19 has become a throny international public health event. As of Mar 24th, China has cumulatively diagnosed 81747 cases and 147 new cases, while the number of...Read More
Since December, 2019, an outbreak of pneumonia caused by a novel coronavirus (SARS-CoV-2) has raised intense attention in Wuhan, Hubei province, China. 1-3 This disease, named COVID-19 by World Health Organization (WHO), spreads rapidly around the country and worldwide. Coronaviruses can infect a variety of livestock, poultry, and humans, in which they can cause respiratory,...Read More
