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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Storz Modulith Shockwave Systems- Mechanisms, Clinical Context, & Alternatives

Storz Modulith Shockwave Machines: Efficacy & Alternatives Explored

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Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

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MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Latest Basic Research Abstracts

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Exploring Regenerative Treatment for Knees After Failed Conservative Care

Regenerative Treatment for Knees That Fail Conservative Care

Effects of Extracorporeal Shockwave Therapy on Patients with Chronic Low Back Pain and Their Dynamic Balance Ability

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Dr. Lohse Bush, first brain treatments

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

ESWT in skin & aesthetic indications

Chattanooga Shockwave Devices Compared- What Clinicians Should Evaluate

Chattanooga Shockwave Therapy Devices Compared

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Sound Frequency Healing: The Spark of Life

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Spark Wave® Therapy Ameliorates Urinary Incontinence

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Shockwave Therapy Of The Heart​

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Effects of Low-Energy Shock Waves on Oral Bacteria

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Best Noninvasive Options for Regenerative Back Treatment Without Injections

Best Options for Regenerative Back Treatment Without Injections

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Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

EPAT Therapy Costs for Patients & Practices

What Is StemWave Therapy? How It Works, What It Costs & How It Compares

Can You Use a Shockwave Therapy Machine at Home?

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Shockwave Therapy: Does it Hurt?

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Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Urological Times Cover – Scroll to Page 18 – 19

Reduce Inflammation Naturally With Shockwave Therapy

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Best Shockwave Machine for Providers

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Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

Fully healed, Ordonez flourished for Tigers using ESWT

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

The Best Alternatives to Rotator Cuff Surgery

Alternatives to Rotator Cuff Surgery

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

How to Improve Podiatry Practice ROI

How to Improve Podiatry Practice ROI

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Alternatives to Surgery

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Athletic therapy (Mts-Science)

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

LL37 and shock waves

Treatment of stress urinary incontinence

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SoftWave Therapy for Knees

SoftWave Therapy vs. Stem Wave & Acoustic Wave Devices for Knee Pain

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

MTS Spark WaveTM Technology and its mechanism of action in wound management

Shockwave Therapy for Achilles Tendonitis

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Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Focused vs Radial Shockwave Therapy Machines Explained 

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

SDSM Spine pain protocol

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

How Li-ESWT Works for Patients With ED & Other Indications

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Shock wave therapy for systemic sclerosis

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Zapping chronic tendon pain

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Managing Pain with Shockwave Therapy for Muscles

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

Treatment of scaphoid waist nonunion

The Physics of Shock Wave Lithotripsy

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Evaluation of extracorporeal shock wave therapy for osteoarthritis

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Novel Approach to Obtain an Activated Fat Graph

Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

SoftWave: Pioneering Shoulder Pain Relief with Advanced Shockwave Therapy

Indications for shockwaves in veterinary medicine

4 U. S. Patents issued on July 19, 2022

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Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

ESWT Therapy for Treatment of Keloid Scars

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Motor and Sensory Schwann Cell Phenotype

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Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Is surgery the only option for bone-on-bone?

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Ultrasound Based Brain Stimulation

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Biological mechanism of musculoskeletal shockwaves

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Shock waves induce angiogenesis via exosome release

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Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

How Shockwave Therapy Breaks Down Scar Tissue

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Erectile Dysfunction before and after results under ultrasound

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

​Extracorporeal shock wave therapy: What? Why? Safety?

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

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Biological Principles – Mechanotransduction

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

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TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Veterinary wound care case study

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Natural Remedies for Tendonitis

Doctor Uses Shockwave Therapy to Heal Nearly Severed Foot

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Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Treatment for osteonecrosis of the femoral head

Cleveland Clinic – Low Intensity Shockwaves In Urology

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

Using acoustic therapy to prevent opioid addiction.

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Extracorporeal shock wave therapy for nonunion of the tibia

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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​The biologic effects of SoftWaves and rationale for spine and brain therapy

Low-energy Extracorporeal Shock Wave Therapy (ESWT) on secondary fibrolymphedema

Mechano-transduction effect of shock waves

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Extracorporeal Shock Wave Therapy

ISMST (International Society for Medical Shockwave Treatment)

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Shockwave Therapy for the Treatment of Cancer

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Scientific Reports – Gene transfection by shock waves

Shock wave application to cell cultures

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DolorClast Therapy- Mechanism, Indications, and Clinical Evidence

DolorClast Therapy: What Is It & Does It Work for Patients?

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

7 Red Flags That Signal a Risky Shockwave Device

Shockwave Therapy for Physical Therapists

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

ISSWSH Abstract

ESWT for resident stress fractures in athletes.

Extracorporeal Shock Wave Therapy: Current Evidence

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

SoftWave Therapy Averts Amputation for Former College Football Coach

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Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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​Exosomes and Cardiovascular Protection

Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

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Ultrasound Brain Stimulation Piloted in Alzheimer Study

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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