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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Neuropathy

Shockwave Therapy for Neuropathy

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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Low Intensity Shockwave Therapy vs High Intensity: Which Works Best?

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Extracorporeal Shockwave Therapy for Arthritis Treatment

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

MTS Spark Wave Publications – Science Telegram

IVSWT Water Bath V2.0 Manual

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

Foot application

Shockwave Therapy for Podiatrists: A Complete Guide

Shock Wave Therapy (MI-ESWT) for Plantar Fasciitis

ESWT for resident stress fractures in athletes.

Molecular changes in diabetics foot ulcers

Physical Rehabilitation Using Shockwave Therapy

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Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Provider demonstrating acoustic wave therapy in a clinical treatment room

Electrohydraulic Shockwave Therapy Explained

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Assessment of IL-1β and VEGF concentration in a rat model during orthodontic tooth movement and extracorporeal shock wave therapy

Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Soft Wave Therapy: An Evidence-Aware Guide

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Dr Irwin Goldstein Dinner Presentation – Nashville

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Shockwave Therapy vs. Ultrasound Therapy

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Benefits of Spark Wave Therapy in neuronal regeneration

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Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

SoftWave Celebrates Pro Success of Golfer Jake Peacock and Baseball Player Reid Worley, Highlighting Injury Prevention Breakthroughs

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Shock waves promote spinal cord repair via TLR32

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Traditional Reimbursement vs Hybrid Practice for Shockwave Providers

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

SoftWave TRT vs Storz Shockwave Machines Compared

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Dr. Lohse Bush, first brain treatments

Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

How to Manage Pain Without Drugs

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Overactive bladder treatment supplies with medication bottle, digital calendar, wearable device, and water glass.

Overactive Bladder Treatment: A Complete Care Guide

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Comparing Shockwave Technologies for Treating Diabetic Foot Ulcers

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Zapping chronic tendon pain

Acoustic Wave Therapy vs Shockwave Therapy

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

Effects of ESWT on glycosaminoglycan expression during bone healing

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Extracorporeal shock wave therapy for nonunion of the tibia

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Shock wave therapy device vs. TENS unit for pain relief and rehabilitation.

Shock Wave Therapy vs TENS: Which Is Best for Pain?

Effect of shockwave therapy on orthodontic tooth movement

Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

​Extracorporeal shock wave therapy: What? Why? Safety?

Effect of shock waves on macrophages

10 Natural Ways to Find Pain Relief

Athletic therapy (Mts-Science)

Government Sales

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Shock wave treatment enhances stemness and preserves multipotency

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Provider’s Guide to Shockwave Therapy for Wound Care

Provider’s Guide to Shockwave Therapy for Wound Care

Shockwave Therapy for Achilles Tendonitis

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Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Macrophage migration induces angiogenesis

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Plantar Fasciitis Medical Devices That Relieve Pain

Does Dermapace Work for Patients?

Professionals discussing premature ejaculation treatment options with medical data on a tablet.

Premature Ejaculation Treatment: An Evidence-Based Guide

Scientific Reports – Gene transfection by shock waves

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Physical therapist guides muscle strain treatment exercises for a patient wearing an arm sling.

Muscle Strain Treatment: Safe Steps for Recovery

Shock Waves Reach Dental Implantology (Spanish)

StemWave Machine: Cost, Reviews & Alternatives for Practice Owners

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Shockwave Therapy for the Treatment of Cancer

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

The Roll of Spark Waves in the Management of Chronic Wounds.

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

OmniWave Shockwave Therapy- Efficacy & Alternatives Explained

OmniWave Shockwave Therapy: Efficacy & Alternatives Explained

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

How Shockwave Therapy Breaks Down Scar Tissue

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

Angiogenic response upon shock wave treatment of the ischaemic muscle

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

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Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

What are the Side Effects of SoftWave Therapy

Alternative Treatment using Shockwave for Erectile Dysfunction

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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Physical therapist assists patient with an arm exercise during a physical therapy session.

Physical Therapy 101: How It Works and What to Expect

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Set up Instructions

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Shock waves induce angiogenesis via exosome release

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Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Biological Principles – Mechanotransduction

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

Treatment for osteonecrosis of the femoral head

Shockwave Therapy for Calcific Tendonitis

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Best Shockwave Machine for Providers

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SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

TRT SoftWaves® – a new regenerative therapy for paraplegia

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Expanding Non-Surgical Options in Podiatry Clinics

The effect of shock waves on in vitro cartilage development in silk scaffolds

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Regenerative Treatments in Sports and Orthopedic Medicine for Clinicians in 2025

Shock wave treatment of muscle stem cells – a new implementation for regeneration

Urological Times Cover – Scroll to Page 18 – 19

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Comprehensive Urology to Utilize New Shockwave Therapy Device: PulseWave

The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

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Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

SoftWave Therapy Averts Amputation for Former College Football Coach

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Treatment of scaphoid waist nonunion

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

7 Red Flags That Signal a Risky Shockwave Device

Can Shockwave Therapy Cause Damage?

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

Current concepts of shockwave therapy in stress fractures

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Knee Pain Relief through Advanced Shockwave Therapy

SoftWave: Leading the Way in Knee Pain Relief through Advanced Shockwave Therapy

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Unfocused extracorporeal shockwave therapy diminishes bone loss in rats

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

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Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

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Antimicrobial peptide LL37/RNA complexes stimulate Toll-like receptor 3 upon shock wave therapy

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

ISMST (International Society for Medical Shockwave Treatment)

Using Sound to Battle Opioid Crisis

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Physical therapist guiding a woman through a leg exercise for sciatica pain.

Physical Therapy Treatment for Sciatica Pain: A Guide

​Prospective randomized phase II trial of accelerated reepithelialization

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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