SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02

SoftWave TRT Lands Prestigious VA Contract Revolutionizing Pain and Wound Management for Veterans

In a significant step forward for veterans' healthcare, SoftWave Tissue Regeneration Technologies (SoftWave TRT) has...

Seven Trends in Healing for 2023

Smith, William The pace of innovation in regenerative medicine keeps getting faster. At clinics across...

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Hausner t. et al.Experimental Neurology, 236(2), 363–370. https://doi.org/10.1016/j.expneurol.2012.04.019. Click here to read more.

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a form of energy transfer that is of...

Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Onger et al.Med Oral Patol Oral Cir Bucal. 2017 Mar 1;22(2):e251-e257.2017 Click here to read...

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

(Tz-Yan Lin, Jing-Ting Chen, Yu-Yu Chen, Tien-Wen Chen , Chia-Ling Lee, Chia-Hsin Chen, Mao-Hsiung Huang)...

Extracorporeal Shockwave Therapy for Kidney Stone Treatment

Kidney stones, a common urological condition causing significant morbidity worldwide, have historically challenged medical professionals...

ESWT in skin & aesthetic indications

ESWT in skin graft epithelialization 3 days faster healing. Click here to read more.

A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

(Balagué et al., 2012). Non-specific low back pain is common and affects people of all...

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Extracorporeal shockwave therapy (ESWT) is used in a number of indications in the medical field....

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Click here to read more.

Physical Rehabilitation Using Shockwave Therapy

Injuries can have a serious impact on lifestyle and health, which means that physical rehabilitation...

Prospective Randomized Trial of Accelerated Re-Epithelization of Skin Graft Donor Sites Using Extracorporeal Shock Wave Therapy

Christian Ottomann, MD, Bernd Hartmann, MD, Josh Tyler, MD, Heike Maier, MD, Richard Thiele, MD,Wolfgang...

Shock waves promote spinal cord repair via TLR32

Click here to read more.

SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

Prof. Hilde Beele (MD), Steven Smet, Francis Ramboer, at Ghent University Hospital faced up to the great...

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice,...

Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether...

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

Click here to read more.

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

(Shih-Feng Lin, Yi-Jen Chen, Hung-Pin Tu , Chia-Ling Lee, Ching-Lin Hsieh , Wen-Lan Wu ,...

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Click here to read more.

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Extracorporeal Shockwave Therapy – ESWT has had a wide use in rehabilitation, and has presented...

The link between shockwaves and innate immunity – the main working mechanism?

Click here to read more.

Latest Basic Research Abstracts

Click here to read more.

EPAT Therapy Costs for Patients & Practices

Extracorporeal Pulse Activation Technology (EPAT) is a non-invasive treatment that uses pressure waves to stimulate...

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

he physical shaking of the tissue by the shock waves leads to a mechanotransduction; the...

Evaluation of extracorporeal shock wave therapy for osteoarthritis

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and...

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the...

Biological mechanism of shockwave in bone

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through...

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Priglinger et al.Cytotherapy. 2017 Sep;19(9):1079-1095. doi: 10.1016/j.jcyt.2017.05.010. Epub 2017 July 19, 2017 Click here to read...

Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectivelyprotect sciatic nerve (SN)...

SoftWave Tissue Regeneration Technologies Receives Innovative Technology Contract from Vizient For DermaGold®

SoftWave Tissue Regeneration Technologies has received an Innovative Technology contract from Vizient, Inc.

Shock Wave Therapy for ED: Does It Work?

For men, erectile dysfunction (ED) can be a challenge, causing feelings of frustration, anxiety, and...

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

We hypothesized that combined treatment with extracorporeal shock wave and bone marrow-derived endothelial progenitor cells...

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Knowing the most effective treatment options for your patients is crucial for their speedy recovery....

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Robert Dymarek, PhD, PT; Tomasz Halski, PhD, PT; Kuba Ptaszkowski, PhD, PT; Lucyna Slupska, PhD,...

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Click here to read more.

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Jieyuan Zhang, Junjie Guan, Xin Niu, Guowen Hu, Shangchun Guo , Qing Li , Zongping...

Shockwave Therapy: Does it Hurt?

At SoftWave we promote healing using shockwave therapy. SoftWave strives to make patients’ lives easier...

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

(Swiss Paraplegic Centre Nottwil) – Spasticity is the most problematic self-reported secondary medical problem in patients...

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Mayo Clinic – Extracorporeal shock wave therapy (ESWT) is a noninvasive treatment that involves delivery of shock...

The Physics of Shock Wave Lithotripsy

Shock wave lithotripsy (SWL) was introduced in the 1980s for the treatment of urinary stones...

Acoustic Wave Therapy vs Shockwave Therapy

If you work with patients who suffer from musculoskeletal issues, you may be familiar with...

Technology Assessment “Wound Care” dermagold100

MTS-Science – Acute wounds are caused exogenously by traumatic (e.g. mechanical, chemical, thermical) or iatrogenic (e.g. surgical)...

STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

In December 2018, STORZ MEDICAL has received the CE approval for the NEUROLITH®, a new...

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Xi Ouyang , Xiaoyan Han , Zehong Chen, Jiafeng Fang, Xuna Huang and Hongbo Wei...

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

Tepeöylü et al.Journal of Tissue Engineering and Regenerative Medicine, 12(1), e486–e494. https://doi.org/10.1002/term.2317.2018 Click here to read...

MTS Science White Paper – Softwave – Pain Therapy

Click here to read more.

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

We tested whether shock wave (SW) offers additional benefits in improving left ventricular (LV) function...

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Previously we have shown that epicardial shock-wave therapy improves left ventricular ejection fraction (LVEF) in...

Urological Times Cover – Scroll to Page 18 – 19

Urological Times – It’s hard to argue against an erectile dysfunction treatment that is potentially...

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

The Surviving Sepsis Campaign panel (ahead of print, DOI: 10.1007/s00134-020-06022-5) recently recommended that “mechanically ventilated...

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

ATLANTA, May 19, 2021 (Newswire) – SoftWave Tissue Regeneration Technologies patented extracorporeal shock wave device called...

Shock wave therapy alone has no impact on cancer growth

Cancer remains one of the leading causes of morbidity and mortality throughout the world. Several...

Alternative Treatment using Shockwave for Erectile Dysfunction

MTS Science Published on Jun 21, 2016 – The improvement of Erectile Dysfunction through the use UroGold...

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar fasciitis, a prevalent foot condition, often manifests as persistent heel pain, particularly acute in...

Treatment of stress urinary incontinence

To investigate the outcomes and mechanisms of low-intensity extracorporeal shock wave therapy (Li-ESWT) on stress...

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Click here to read more.

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal...

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

The objective of this study is to demonstrate the efficacy and safety of AWT(®), combining two different mechanical...

Extracorporeal shockwave therapy for treatment of keloid scars

Center for Shockwave Medicine and Tissue Engineering, Department of Orthopedic Surgery/Sports Medicine, Kaohsiung Chang Gung...

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The...

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Zimpfer D, Aharinejad S, Holfeld J, et al.J Thorac Cardiovasc Surg. 2009; 137(4):963-970 Click here to...

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

(Alexandra Aicher, MD; Christopher Heeschen, MD; Ken-ichiro Sasaki, MD; Carmen Urbich, PhD; Andreas M. Zeiher,...

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Stojadinovic A, Elster E, Anam EA, et al.Angiogenesis. 2008; 11(4):369-380 Alexander Stojadinovic 1, Eric A Elster, Khairul Anam, Douglas Tadaki, Mihret...

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Mittermayr R, Antonic V, Hartinger J et al .Wound Repair Regen. 2012 Jul;20(4):456-65 Click here to...

Spark Wave® Therapy Ameliorates Urinary Incontinence

MTS-Science April 14th, 2019. Stress urinary incontinence (SUI) is the involuntary leakage of urine during activities such...

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

In this randomized, placebo-controlled clinical trial, we investigated the effect of noninvasive extracorporeal shock waves...

Shockwave Therapy for the Treatment of Cancer

Breast cancer is characterized by rapid aberrant growth of tissue in the mammary glands. The speed...

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Kenneth Craig Vincent, Wolfgang Schaden, Laupepa Aposetolo Karalus, Jacqueline Craig Huges, Daniel Poratt – The ‘Niche’ is...

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

SoftWave® Tissue Regeneration Technologies, a disruptive bio-medical device company, announces the beginning of a trial...

Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

In this prospective design study the effects of low-energy partially focusedextracorporeal generated shock waves (ESW)...

Prospective randomized phase II trial of accelerated reepithelialization

Christian Ottomann, MD, Alexander Stojadinovic, MD, FACS, Philip T. Lavin, PhD,§ Francis H. Gannon, MD,...

Indications for shockwaves in veterinary medicine

Click here to read more.

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

Shockwave therapy (SWT) represents a promising regenerative treatment option for patients with ischemic cardiomyopathy. Although...

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Dental implants are a routine procedure within the therapeutic range of dentists. Many loading protocols...

Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant...

Cleveland Clinic – Low Intensity Shockwaves In Urology

Cleveland Clinic Daniel Shoskes, MD – As urologists, we have decades of experience with extracorporeal shockwave lithotripsy for...

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Hercher et al.TERMIS World Congress 2018 in Kyoto, Japan Click here to read more.

Shockwave therapy in stress fractures

Stress fractures are common painful conditions in athletes, usually associated to biomechanical overloads. Low risk stress...

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Click here to read more.

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

Click to read more.

The Roll of Spark Waves in the Management of Chronic Wounds.

Antibiotic-resistant bacterial colonies often produce biofilms (a defensive mechanism that creates a physical protective barrier...

LL37 and shock waves

Click here to read more.

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

PubMed (Urology Department, Sheba Medical Center, Ramat-Gan, Israel; Ruth and Bruce Rappaport Faculty of Medicine,...

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

Low bone mineral density (BMD) leads to metaphyseal fractures, which are considered of delayed, qualitatively...

CLEARANCES

Lithotriptor, Extracorporeal Shock-Wave, Urological – LithoGoldMassager, Therapeutic, Electric – DermaGold; OrthoGold; UroGoldMassager, Therapeutic, Electric –...

Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

The main aim of our research in this field is to regenerate infarcted myocardium, respectively...

Macrophage migration induces angiogenesis

Holfeld et al. Thorac. Cardiovasc. Surg. (2012). doi:10.1055/s-0031-1297858 Click here to read full article – Macrophage...

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Cellulite is a multifactorial condition that is present in 80-90 % of post-pubertal women, commonly found...

Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

(Non-invasive treatment of herniated discs by focused shockwave therapy) – In orthopedic practice meets a number...

Unfocused extracorporeal shock waves induce anabolic effects in osteoporotic rats

Van der Jagt et al.Journal of Orthopaedic Research, 31(5), 768–775. https://doi.org/10.1002/jor.22258. Click here to read more.

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Patients with probable Alzheimer disease (AD) had sustained memory improvements months after ultrasound brain stimulation...

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial

This randomized clinical trial investigated the effect of extracorporeal shock waves on the amount of...

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Patients with systemic sclerosis (SSc) often display Raynaud’s phenomenon and digital skin ulcers. As these...

Cellular mechanotransduction: putting all the pieces together again

Vascular Biology Program, Departments of Pathology and Surgery, Harvard Medical School and Children’s Hospital, Boston,...

EPAT Therapy Side Effects & Contraindications

Extracorporeal Pulse Activation Technology (EPAT) is a prominent form of shockwave therapy that leverages radial...

Antibacterial effects of extracorporeal shock waves

Klinik und Poliklinik für Orthopädie und Sportorthopädie der Technischen Universität München, München, Germany; and Institut...

Shockwave Therapy Of The Heart

Ischemic heart disease represents a collective term for a continuous disease pathophysiology, ranging from acute...

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from...

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

(Wei Wei, Hua-yu Tang, Yu-zhi Li, Tian-shu Wang) – : Previous clinical trials have reported that...

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Ottomann C, Hartmann B, Tyler j, et al.J Am Coll Surg. 2010; 211(3):361-7 Click here to...

Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Click here to read more.

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor...

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...

Stem cells pose risk, offer promise

Providing the therapy involves using an FDA cleared device with “genuine” shock waves, according to...

Extracorporeal shock wave therapy: clinical applications and regulation

Shock wave therapy is a relatively new modality for use in equine practice. The application...

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Fracture non-unions are still a challenging problem in orthopedics. The treatment of non-unions remains highly...

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Low-energy extracorporeal shock wave treatment (ESWT) is a relatively new therapeutic tool that is widely...

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

CREST syndrome is a variant of systemic sclerosis, which affects a relatively small number of...

ESWT for resident stress fractures in athletes.

Stress fractures are major concerns with athletes. It is sometimes difficult to repair, resulting in...

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

A phase III, randomized, double blind controlled with placebo study – (MTS-Science) – Chronic Prostatitis/ Chronic...

ESWT for retracting scars of the hand

Department of Medical Sciences, Oral and Biotechnology, ‘‘G. D’Annunzio’’ University, Chieti, Italy; Department of Dermatology,...

Shock wave treatment of muscle stem cells – a new implementation for regeneration

Fuchs et al. 20th ISMST Congress in San Sebastian, Spain Abstract P29 Click here to...

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

High energy diaphyseal fractures constitute a complicated matter for trauma units and urgent medical and...

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

We report the case of a 78-year-old woman with a history of hypertension, deep vein...

Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

(MTS Science) – Peripheral nerve injuries affect millions of people every year. After trauma or surgery, patients...

Principles of Shock Wave Therapy

John A. Ogden, MD; Anna Tóth-Kischkat, PhD; and Reiner Schultheiss, PhD Click here to read...

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated...

Extracorporeal shock wave therapy: What? Why? Safety?

Click here to read more.

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Schaden W, Thiele R, Kolpl C, et al.J Surg Res. 2007; 143:1-12 Click here to read...

Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost...

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Eric Chung, University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane, AndroUrology Centre, St...

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Cyrill Slezak Beijing, May 24TH, 2019 Click here to read more.

Dr Irwin Goldstein Dinner Presentation – Nashville

Click here to read more.

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

MTS-Science – SparkWave™ therapy (SW™T) is a modern day non-invasive treatment option for a wide range...

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Extracorporeal shock wave therapy (ESWT) uses acoustic pulses to treat certain musculoskeletal disorders. In this...

Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Human bone marrow stromal cells (hBMSCs) bear tremendous clinical potential due to their immunomodulatory properties...

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Anna M Larking, Sophie Duport Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, Michael Clinton...

The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria; AUVA Trauma Center Meidling, Vienna, Austria; ...

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Click here to read more.

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

(Dr Irwin Goldstein MD) Analogy to blood flow imparting physical forces – shear stress – onto...

Case Series of Low Intensity Shock Wave Therapy for Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Shoskes et al., Cleveland Clinic, United StatesAUA Congress in Lisbon, Portugal Click here to read...

SoftWave TRT Selected to Exhibit DermaGold at Vizient Innovative Technology Exchange

SoftWave TRT has been selected to exhibit at the Vizient Innovative Technology Exchange.

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Karsten Knobloch • Beatrice Joest • Robert Kra ̈mer • Peter M. Vogt – Focused extracorporeal shockwave...

Shock wave treatment enhances stemness and preserves multipotency

Schuh et al.Cytotherapy, 16(12), 1666–1678. https://doi.org/10.1016/j.jcyt.2014.07.005. Click here to read full article on In vitro extracorporeal...

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

Click here to read more.

Reduce Inflammation Naturally With Shockwave Therapy

Like all things, inflammation is good and healthy in moderation, but when it becomes chronic,...

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

d’Agostino MC., Sukubo NG., Tibalt W., Respizzi S., Locati M.,Int J Surg. 2015 Dec; 1-72015 Click...

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

To evaluate the effect of extracorporeal shockwave therapy (ESWT) on pain and function in myofascial...

Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

This study aimed to evaluate the therapeutic effects of Low intensity extracorporeal low energy shock...

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process...

Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

It has been hypothesized that there are two mechanisms of acute traumatic spinal cord injury...

How Does Shockwave Therapy Work?

If you are a healthcare provider, you likely prescribe a variety of treatments to help...

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Ottomann C., Antonic V., Münch S., et al.J Bioengineer & Biomedical Sci 2015, 6:12015 Click here...

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

Accelerated tooth movement has been a topic of interest for orthodontic research recently. Surgically facilitated...

Novel Approach to Obtain an Activated Fat Graph

One of the mainstays of facial rejuvenation strategies is volume restoration, which can be achieved...

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

This RCT investigated the effect of non-invasive extracorporeal shockwaves on tooth mobility in orthodontic patients...

Sound Frequency Healing: The Spark of Life

By: Dr. Matt DiDuro How Sound Frequency Healing Works SoftWave’s sound frequency healing technology, known...

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Cell-based therapies with autologous adipose tissue–derived cells have shown great potential in several clinical studies...

Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue...

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

The stromal vascular fraction (SVF) is a heterogeneous cell population derived from the adipose tissue....

Alternatives to Cortisone Shots

If you have a patient with debilitating joint pain, you may have recommended or administered...

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

Fleckenstein et al.Arch. Phys. Med. Rehabil. 98, 923–930 (2017). Click here to read more.

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Grzegorz Lukasz Fojeck · Stefan Tiessen · Palle Jörn Sloth Osther 2017 – The objective was...

Analysis of treatment protocols: application of ESWT for wound healing disorders

Shock waves are high-energy acoustic waves characterized by an initial rise of high pressure within...

Biological Principles – Mechanotransduction

Click here to read more.

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...

Penile low-intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic erectile dysfunction since 2-10 years: A prospective, randomized, placebo-controlled study

Vinay et al., Fundació Puigvert, Barcelona, Spain 20th ISMST Congress in San Sebastian, Spain Click...

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

We prospectively studied extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder in...

Best Treatment for Tennis Elbow Relief

What is Tennis Elbow and What Causes It? Even if you’re not an avid tennis...

Exosomes and Cardiovascular Protection

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called...

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Yard DH.Renal & Urology News. 2011 Click here to read more.

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Van der Jagt et al.Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society,...

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Wolff et al.Ultrasound Med Biol. 2011 Jul;37(7):1111-9. Click here to read more.

Ultrasound Based Brain Stimulation

Ultrasound based brain stimulation techniques bay become a powerful new technique to modulate the human...

Shockwave Therapy for Achilles Tendonitis

Achilles tendonitis is a common condition that causes pain and swelling in the Achilles tendon,...

Extracorporeal Shockwave Therapy for Arthritis Treatment

Arthritis stands as a prevalent chronic joint condition, significantly impacting the quality of life for...

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Mesenchymal stem cells are regarded as common cellular precursors of the musculoskeletal tissue and are...

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

MTS Medical – First comparative report for MTS/TRT UroGold, (unfocused shockwaves “SoftWaves” ) and Radial/Ballistic waves,...

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany)

The aim of this meta analysis was to investigate the effectiveness of extracorporeal shock wave...

Is surgery the only option for bone-on-bone?

Patients are stuck and searching for non-surgical alternatives. SoftWave is a cost-effective alternative to joint...

SoftWave vs Shockwave Technology Explained

In the dynamic world of medical advancements, SoftWave and Shockwave technologies stand out as pivotal...

Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions

Predictive models permitting individualized prognostication for patients with fracture nonunion are lacking. The objective of...

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Shogo Inoue, Tetsutaro Hayashi, Jun Teishima, Akio Matsubara Click here to read full article on...

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

Extracorporeal shockwave treatment was shown to improve orthopaedic diseases and wound healing and to stimulate...

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into...

Response of Post-Mastectomy Lymphedema to Extracorporeal Shockwave Therapy

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt Department of General...

In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Schuh et al. 4th ISMST Basic Research Meeting in Vienna, Austria Click here to read...

Equine extracorporeal shock wave therapy

Extracorporeal shock wave therapy (ESWT) is an accepted form of treatment for chronic cases of...

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

MTS-Science Low-intensity extracorporeal shock wave therapy (LI-ESWT) is of great clinical interest for the treatment...

4 U. S. Patents issued on July 19, 2022

SoftWave officially has been granted 4 new patents as of July 19, 200. They include...

OrthoGold 100TM

Click here to read more.

Shock wave therapy for osteoinduction

Koolen et al. 20th ISMST Congress in San Sebastian, Spain Abstract P33 Click here to...

Doubts over heart stem-cell therapy

The cells are then injected back into the patient, to help repair damaged tissue. Original...

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Saggini R., Saggini A., Spagnoli A.M.Ultrasound in Med. & Biol. Vol. 42, No. 1, pp....

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

RESULT Among 187 patients with confirmed COVID-19, 144 patients (77%) were discharged and 43 patients...

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

Powerpoint abstract. Click here to read more.

Optimization of screw fixation in rat bone with extracorporeal shock waves

Koolen et al.Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23615. Click here to read more.

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...

The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Saggini et al. Int J Pharma Sci Res 2016, 3: 119 Click here to read more.

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

This study aims to evaluate the effects of extracorporeal shock wave therapy applied before and/or...

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Click here to read more.